2,4-二硝基氯苯 → 2-(2,4-二硝基苯氧基)乙醇

HRID 1531477

反应方程式

HRID 1531477 反应方程式
[C:1]([O-:5])(=O)[CH2:2][OH:3].C=C.[Na+].[N+:9]([C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1Cl)([O-:11])=[O:10].O>C(O)CO>[N+:9]([C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1[O:3][CH2:2][CH2:1][OH:5])([O-:11])=[O:10]

参与物

5

反应物 3

HCID 62,4-二硝基氯苯HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]HCID 23717809Mono sodium ethylene glycolate2 次

产物 1

HCID 760702-(2,4-二硝基苯氧基)乙醇收率 92.2%

试剂、催化剂与溶剂 1

HCID 1742,2’-[(1-甲基亚乙基)二(4,1-亚苯基氧亚甲基)]二环氧乙烷与α-氢-ω-羟基聚(氧-1,2-亚乙基)的聚合物溶剂2 次

反应条件

温度
65 °C

实验过程

200 ml of ethylene glycol and 40 ml of a 14.4% strength mono-sodium ethylene glycolate solution were introduced initially under nitrogen and were heated to 65° C. in a 2 l reaction vessel fitted with a stirrer. Over the course of 5 h, 162 g of molten 2,4-dinitrochlorbenzene and a further 480 ml of a 14.4% strength mono-sodium ethylene glycolate solution in ethylene glycol were simultaneously metered in. The mixture was then stirred for one hour at 65° C., and then 600 ml of water were added. The precipitate which formed was filtered off and washed with 1000 ml of water and dried, giving 161.3 g of 2-(2′,4′-dinitrophenoxy)-ethanol in a purity of 97%. Hence, a yield of 92.2% is achieved based on 2,4-dinitrochloro-benzene.

后处理

  1. customfitted with a stirrer
  2. customThe precipitate which formed
  3. filtrationwas filtered off
  4. washwashed with 1000 ml of water
  5. customdried

来源与证据

ORD记录
ord-d1b19539d0164fdd89d11238c9ff9c7c
来源数据集
uspto-grants-2001_03
专利号
US06198007B1

关联笔记

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