N,N'-二异丙基碳二亚胺 → 苯基硫脲

HRID 1660670

反应方程式

HRID 1660670 反应方程式
C([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([NH2:13])=[S:12])=[CH:6][CH:5]=1)(O)=O.CC(C)N=C=NC(C)C>CN(C=O)C>[C:7]1([NH:10][C:11]([NH2:13])=[S:12])[CH:8]=[CH:9][CH:4]=[CH:5][CH:6]=1

参与物

4

反应物 2

HCID 12734N,N'-二异丙基碳二亚胺HCID 736216(4-羧苯基)硫脲

产物 1

HCID 676454苯基硫脲

试剂、催化剂与溶剂 1

HCID 6228N,N-二甲基甲酰胺溶剂

实验过程

4-carboxyphenylthiourea (Lancaster, 13047) was dissolved to 0.2M in DMF. The resultant mixture was activated by adding a half equivalent of DIC for 15 min at room temperature. Aminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) were coated with the activated solution thus obtained and incubated for three hours at room temperature. The glass surfaces thus treated were then washed five times using respectively 30 mL of DMF for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

后处理

  1. customAminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651)
  2. customthus obtained
  3. additionThe glass surfaces thus treated
  4. washwere then washed five times
  5. customfor 3 minutes
  6. customat room temperature
  7. washAfter washing three times for three minutes each using respectively 30 mL of DCM at room temperature
  8. customthe glass surfaces were dried
  9. customstored at 4° C. until further use

来源与证据

ORD记录
ord-41314afdd5c447e7aa8917fc1c6e8c11
来源数据集
uspto-grants-2011_10
专利号
US08029979B2

关联笔记

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