聚乙内酰脲 → DL-苯丙氨酸

HRID 1958

反应方程式

HRID 1958 反应方程式
O=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11]O)O)O)O)O.[NH2:13][C@H:14]([C:16]([OH:18])=[O:17])[CH3:15]>>[NH2:13][C@@H:14]([C:16]([OH:18])=[O:17])[CH2:15][C:2]1[CH:11]=[CH:9][CH:7]=[CH:5][CH:3]=1.[NH2:13][C@H:14]([C:16]([OH:18])=[O:17])[CH2:15][C:2]1[CH:11]=[CH:9][CH:7]=[CH:5][CH:3]=1

参与物

4

反应物 2

HCID 5950聚乙内酰脲2 次HCID 107526D-葡萄糖-UL-14C

产物 2

HCID 6140DL-苯丙氨酸HCID 71567D-苯丙氨酸

实验过程

The amount of glucose fed was 2021 g over 52 hours. The fermentation medium included a D-, L-alanine feed whereby a total of 1400 mls of 167 g/l D-, L-alanine was fed at a rate of 1.9 ml/min starting 12 hrs from the beginning of the fermentation. In addition, L-phenylalanine was fed at the same concentration and rate as the D-, L-alanine. The fermentation resulted in 13.66 g/l of D-phenylalanine and 0.87 g/l L-phenylalanine being produced.

后处理

  1. customover 52 hours
  2. concentrationIn addition, L-phenylalanine was fed at the same concentration and rate as the D-, L-alanine

来源与证据

ORD记录
ord-ca050bcf3e3041878a46906ef366ed6a
来源数据集
uspto-grants-1998_03
专利号
US05728555

关联笔记

加载中…