7-氟吲哚 → 7-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

HRID 1993211

反应方程式

HRID 1993211 反应方程式
Cl[C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:7]2.[F:20]C1C=CC=C2C=1NC=C2>>[F:20][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:7]2

参与物

3

反应物 2

HCID 27745047-氟吲哚HCID 532172117-CHLOROINDOLE-2-BORONIC ACID, PINACOL ESTER

产物 1

HCID 591331527-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

实验过程

Prepared according to a procedure analogous to that described for 7-chloro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole using 7-fluoro-1H-indole.

后处理

  1. customPrepared

来源与证据

ORD记录
ord-97608e9a31c44268a467f9567fe00832
来源数据集
uspto-grants-2010_01
专利号
US07651687B2

关联笔记

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