5-ó2-(三氟甲氧基)苯基-2-糠醛 → 2-Methyl-N-{3-[1-((5-[2-(trifluoromethoxy)phenyl]-2-furyl}methyl)-4-piperidinyl]phenyl}propanamide

HRID 2087384

反应方程式

HRID 2087384 反应方程式
[F:1][C:2]([F:18])([F:17])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[O:14][C:13]([CH:15]=O)=[CH:12][CH:11]=1.[CH3:19][CH:20]([CH3:36])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:25]=1)=[O:22]>>[CH3:19][CH:20]([CH3:36])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]2[CH2:35][CH2:34][N:33]([CH2:15][C:13]3[O:14][C:10]([C:5]4[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=4[O:3][C:2]([F:1])([F:17])[F:18])=[CH:11][CH:12]=3)[CH2:32][CH2:31]2)[CH:25]=1)=[O:22]

参与物

3

反应物 2

HCID 7218385-ó2-(三氟甲氧基)苯基-2-糠醛HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

产物 1

HCID 220491582-Methyl-N-{3-[1-((5-[2-(trifluoromethoxy)phenyl]-2-furyl}methyl)-4-piperidinyl]phenyl}propanamide

实验过程

Prepared by Procedure F and Scheme R using 5-[2-(trifluoromethoxy)phenyl]-2-furaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 487.1 (M+H)+.

后处理

  1. customPrepared by Procedure F and Scheme R

来源与证据

ORD记录
ord-87168d5eaa834ace9ba5e185c80aa05b
来源数据集
uspto-grants-2004_04
专利号
US06727264B1

关联笔记

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