氯乙酰氯 → 4-氯-N'-(2-氯乙酰基)苯甲酰肼

HRID 2185

反应方程式

HRID 2185 反应方程式
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[Cl:12][CH2:13][C:14](Cl)=[O:15]>O1CCOCC1>[Cl:12][CH2:13][C:14]([NH:9][NH:8][C:6](=[O:7])[C:5]1[CH:10]=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:15]

参与物

4

反应物 2

HCID 6577氯乙酰氯HCID 108164-氯苯甲酰肼

产物 1

HCID 5212924-氯-N'-(2-氯乙酰基)苯甲酰肼

试剂、催化剂与溶剂 1

HCID 312751,4-二氧六环溶剂

实验过程

To a solution of p-chlorobenzoic hydrazide (11.2 g) in dioxane (100 ml) was added chloroacetyl chloride (6 ml). The resulting mixture was refluxed for three hours, cooled to room temperature and filtered. The resulting solid was washed with ethyl ether and dried to yield N'-chloroacetyl-4-chlorobenzoic hydrazide as white solid.

后处理

  1. temperatureThe resulting mixture was refluxed for three hours
  2. filtrationfiltered
  3. washThe resulting solid was washed with ethyl ether
  4. customdried

来源与证据

ORD记录
ord-d38b7b009446439cb95143c67e49b8ed
来源数据集
uspto-grants-1998_03
专利号
US05728715

关联笔记

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