6-乙基屈 → 12-Ethyl-6-chrysenecarbaldehyde

HRID 2413592

反应方程式

HRID 2413592 反应方程式
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:14](=[C:15]3[C:20]=1[CH:19]=[CH:18][CH:17]=[CH:16]3)[CH:13]=[CH:12][C:11]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]2=1)[CH3:2].C1C2C=CC3C(=CC([CH:39]=[O:40])=C4C=3C=CC=C4)C=2C=CC=1>C(Cl)Cl>[CH2:1]([C:3]1[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:14]2[C:5](=[C:6]3[C:11](=[C:12]([CH:39]=[O:40])[CH:13]=2)[CH:10]=[CH:9][CH:8]=[CH:7]3)[CH:4]=1)[CH3:2]

参与物

4

反应物 2

HCID 759516-乙基屈HCID 124387746-Chrysenecarbaldehyde

产物 1

HCID 1337539012-Ethyl-6-chrysenecarbaldehyde收率 76%

试剂、催化剂与溶剂 1

HCID 6344二氯甲烷溶剂

实验过程

6-Ethylchrysene (Cambridge Chemical, Inc., 60 g, 0.234 mol) was formylated according to the procedure outlined in 1A, except that CH2Cl2 (1 L) was used as the reaction solvent. The crude material was chromatographed on a plug of SiO2 (1 kg) using PhCH3 as the eluting solvent, afforded 50.38 g (76%) of 12-ethyl-6-chrysenecarbaldehyde mp 138°-139°, (C,H).

后处理

  1. customThe crude material was chromatographed on a plug of SiO2 (1 kg)

来源与证据

ORD记录
ord-28b4537d92374427b349def21a22c385
来源数据集
uspto-grants-1988_01
专利号
US04719048

关联笔记

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