海萝胶 → 3-(1-吡咯烷甲基)苯甲酸盐酸盐

HRID 2427243

反应方程式

HRID 2427243 反应方程式
C[O:2][C:3](=[O:16])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][N:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)[CH:5]=1.[ClH:17]>>[ClH:17].[N:11]1([CH2:10][C:6]2[CH:5]=[C:4]([CH:9]=[CH:8][CH:7]=2)[C:3]([OH:16])=[O:2])[CH2:15][CH2:14][CH2:13][CH2:12]1

参与物

3

反应物 2

HCID 313海萝胶HCID 534296373-(1-吡咯烷基甲基)苯甲酸甲酯

产物 1

HCID 185258743-(1-吡咯烷甲基)苯甲酸盐酸盐

实验过程

A solution of 3-pyrrolidin-1-ylmethyl-benzoic acid methyl ester (800 mg, 3.6 mmol) in aqueous 25% hydrochloric acid (15 mL) was stirred at 90° C. for 4 hours. The solvent was evaporated affording the title compound as brown oil (quantitative) that was used as such for the next step.

后处理

  1. customThe solvent was evaporated

来源与证据

ORD记录
ord-8cda23d7871149ac9cf399e9f52cbf07
来源数据集
uspto-grants-2011_06
专利号
US07968583B2

关联笔记

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