1-硝基蒽醌 → 1-环己氨基-9,10-蒽二酮

HRID 261007

反应方程式

HRID 261007 反应方程式
[N+:1]([C:4]1[C:17]2[C:16](=[O:18])[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9](=[O:19])[C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-])=O.[CH:20]1(N)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>CC1C=CC(C(C)C)=CC=1>[CH:20]1([NH:1][C:4]2[C:17]3[C:16](=[O:18])[C:15]4[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=4)[C:9](=[O:19])[C:8]=3[CH:7]=[CH:6][CH:5]=2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1

参与物

4

反应物 2

HCID 67041-硝基蒽醌HCID 7965环己胺

产物 1

HCID 706691-环己氨基-9,10-蒽二酮收率 94%

试剂、催化剂与溶剂 1

HCID 74634-异丙基甲苯溶剂

实验过程

25.3 g of 1-nitroanthraquinone (99% pure) in 120 ml of p-cymene are boiled together with 29.8 g of cyclohexylamine (molar ratio 3:1) for 2 hours under reflux. After cooling the reaction mixture, 150 ml of petroleum ether are added, the mixture is filtered and the residue is washed with petroleum ether and dried. 28.1 g (94% of theory) of cyclohexylamino-anthraquinone are obtained. No further starting material can be detected by means of thin layer chromatography.

后处理

  1. temperatureunder reflux
  2. additionare added
  3. filtrationthe mixture is filtered
  4. washthe residue is washed with petroleum ether
  5. customdried

来源与证据

ORD记录
ord-ff7db9d3e9404a2caf01d3b13cb2559f
来源数据集
uspto-grants-1979_08
专利号
US04163747

关联笔记

加载中…