反应方程式
OC1CCC(C)(C)C2C=C(C#CC3C=CC(C(OCC)=O)=CC=3)C=CC1=2.[CH3:27][C:28]1([CH3:52])[C:37]2[CH:36]=[CH:35][C:34]([C:38]#[C:39][C:40]3[CH:50]=[CH:49][C:43]([C:44]([O:46][CH2:47][CH3:48])=[O:45])=[CH:42][CH:41]=3)=[CH:33][C:32]=2[C:31](=[O:51])[CH2:30][CH2:29]1>>[OH:51][CH:31]1[CH2:30][CH2:29][C:28]([CH3:27])([CH3:52])[C:37]2[CH:36]=[CH:35][C:34]([C:38]#[C:39][C:40]3[CH:41]=[CH:42][C:43]([C:44]([O:46][CH2:47][CH3:48])=[O:45])=[CH:49][CH:50]=3)=[CH:33][C:32]1=2参与物
3
反应物 2
产物 1
实验过程
Employing the same general procedure as for the preparation of ethyl 4-[(5,6,7,8-tetrahydro-5-hydroxy-8,8-dimethylnaphth-2-yl ) ethynyl ]benzoate (Compound 9), 1 g (2.88 mmol) of ethyl 4-[(5,6,7,8-tetrahydro-8,8-dimethyl-5-oxonaphth-3-yl ) ethynyl ]benzoate (Compound 2) was converted into the title compound using 60 mg (1.6 mmol) of sodium borohydride.
来源与证据
- ORD记录
- ord-88c53c36b3bf4896b0411a20795a2ed9
- 来源数据集
- uspto-grants-1997_07
- 专利号
- US05648514
关联笔记
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