乙醇钠 → ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6carboximidate

HRID 35157

反应方程式

HRID 35157 反应方程式
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16]#[N:17])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH3:18][CH2:19][O-:20].[Na+]>C(O)C>[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:17])[O:20][CH2:19][CH3:18])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

参与物

4

反应物 2

HCID 2723922乙醇钠HCID 198338865,7-dihydro-6H-dibenz[c,e]azepine-6carbonitrile

产物 1

HCID 19833914ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6carboximidate

试剂、催化剂与溶剂 1

HCID 702乙醇溶剂

实验过程

starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and sodium ethylate in ethanol there is obtained ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate and therefrom with hydrochloric acid in alcohol there is obtained the hydrochloride, m.p. 158° C. (with decomposition);

来源与证据

ORD记录
ord-ad64697779764f5296b06bd50992d95c
来源数据集
uspto-grants-1988_08
专利号
US04766115

关联笔记

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