三正丁胺 → 六氟异丁烯

HRID 35390

反应方程式

HRID 35390 反应方程式
C(N(CCCC)CCCC)CCC.[F:14][C:15]([F:27])([F:26])[CH:16]([C:22]([F:25])([F:24])[F:23])[C:17](OCCl)=O>>[F:14][C:15]([F:27])([F:26])[C:16]([C:22]([F:25])([F:24])[F:23])=[CH2:17]

参与物

3

反应物 2

HCID 7622三正丁胺HCID 13954659Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate

产物 1

HCID 91450六氟异丁烯收率 75.9%

反应条件

温度
65 °C

实验过程

In a four necked 100 ml flask equipped with a condenser, a dropping funnel and a thermometer, tributylamine (20.0 g, 108 mmoles) was charged and warmed to 65° C. Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate (4.88 g, 20 mmol) was dropwise added thereto while stirring. The reaction was continued at the same temperature as above for 3 hours while stirring. The gas evolved from a top of the condenser was washed with an alkaline solution, dried with alumina and cooled. The resultant liquid was distilled to give 2-trifluoromethyl-3,3,3-trifluoropropene (2.49 g). Yield, 76 %.

后处理

  1. customIn a four necked 100 ml flask equipped with a condenser, a dropping funnel
  2. customwas continued at the same temperature as above for 3 hours
  3. stirringwhile stirring
  4. washwas washed with an alkaline solution
  5. customdried with alumina
  6. temperaturecooled
  7. distillationThe resultant liquid was distilled

来源与证据

ORD记录
ord-d57e115760924d43a21fc3df3125c5f3
来源数据集
uspto-grants-1988_08
专利号
US04766238

关联笔记

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