水杨酸 → 5-(2-Propylpentanoyl)Salicylic Acid

HRID 35510

反应方程式

[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:11]([CH:14]([CH2:18][CH2:19][CH3:20])[C:15](Cl)=[O:16])[CH2:12][CH3:13]>>[CH2:11]([CH:14]([CH2:18][CH2:19][CH3:20])[C:15]([C:7]1[CH:8]=[C:2]([C:1]([OH:10])=[O:9])[C:3]([OH:4])=[CH:5][CH:6]=1)=[O:16])[CH2:12][CH3:13]

参与物

反应物 2

HCID 338水杨酸

HCID 762402,2-二-正丙基乙酰基氯

产物 1

HCID 137487105-(2-Propylpentanoyl)Salicylic Acid收率 52%

实验过程

This compound is prepared by a Friedel-Crafts reaction from salicylic acid and 2-propylpentanoyl chloride. The acid yield is 52%. The recrystallization is done in petroleum ether. The melting point is 118° C.

后处理

customThe recrystallization

来源与证据

ORD记录: ord-6261f72d624144a1932153c5569dbb6b
来源数据集: uspto-grants-1988_08
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US04767750

关联笔记

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