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1-(2-氨乙基)哌啶 → 3-[(2-fluoro-4-iodophenyl)amino]-N-(2-piperidin-1-ylethyl)isonicotinamide
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 1-(2-氨乙基)哌啶 | HCID 33944 | — |
| 反应物 | 3 - (2 - 氟-4 - 碘苯基氨基)异烟酸 | HCID 59026791 | — |
| 产物 | 3-[(2-fluoro-4-iodophenyl)amino]-N-(2-piperidin-1-ylethyl)isonicotinamide | HCID 11518392 | — |
反应步骤
3-[(2-fluoro-4-iodophenyl)amino]-N-(2-piperidin-1-ylethyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 2.5 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 4.0 mmol of 2-piperidin-1-ylethylamine. LC/MS [5.40 min; 469 (M+1)]
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US08524911B2 |
| 来源数据集 | uspto-grants-2013_09 |
| ORD ID | ord-40d5dff0e369493e944fe158bf89f750 |
| 来源说明 | uspto-grants-2013_09 |