4-氨基哒嗪 → HCID 71294494，化合物

HRID 469799

反应方程式

HRID 469799 反应方程式
[CH:1]1([C:6]2[C:7]([O:15][CH2:16][C:17]([F:20])([F:19])[F:18])=[N:8][CH:9]=[C:10]([CH:14]=2)[C:11]([OH:13])=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[N:21]1[CH:26]=[CH:25][C:24]([NH2:27])=[CH:23][N:22]=1>>[CH:1]1([C:6]2[C:7]([O:15][CH2:16][C:17]([F:20])([F:19])[F:18])=[N:8][CH:9]=[C:10]([CH:14]=2)[C:11]([NH:27][C:24]2[CH:25]=[CH:26][N:21]=[N:22][CH:23]=2)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5]1

参与物

3

反应物 2

HCID 2984924-氨基哒嗪HCID 712941865-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid

产物 1

HCID 71294494HCID 71294494，化合物

实验过程

This compound was prepared following the same procedure as described in Example 11 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 9c) (100 mg, 0.35 mmol) and 4-pyridazinamine (CAN 20744-39-2, 39.5 mg, 0.41 mmol) as starting materials; off white solid (12 mg, 9.5%). MS (ESI): 367.2 (M+H)+.

后处理

  1. customThis compound was prepared

来源与证据

ORD记录
ord-a0995aaab2cc4c299a2fd5e1d071176f
来源数据集
uspto-grants-2014_01
专利号
US08629166B2

关联笔记

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