H-LEU-PHE-OH → H-PHE-LEU-OH

HRID 547244

反应方程式

HRID 547244 反应方程式
[NH:1]1[C:18](=[O:19])[C@H:10]([CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[NH:9][C:7](=[O:8])[C@@H:2]1[CH2:3][CH:4]([CH3:6])[CH3:5].N[C@H](C(N[C@H](C(O)=O)CC1C=CC=CC=1)=[O:27])CC(C)C>>[NH2:9][C@H:10]([C:18]([NH:1][C@H:2]([C:7]([OH:27])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

参与物

3

反应物 2

HCID 6992310H-LEU-PHE-OHHCID 7076347环(L-亮氨酰-L-苯丙氨酰)

产物 1

HCID 76808H-PHE-LEU-OH

实验过程

As a result, it was confirmed that 6.8 mg/l cyclo(L-Leu-L-Phe), 28.7 mg/l L-Leu-L-Phe and 18.5 mg/l L-Phe-L-Leu were formed. No cyclodipeptide or dipeptide was detected in the reaction mixture when without ATP incubated in the same manner.

来源与证据

ORD记录
ord-308264341c9e44aca6951d5c5965b720
来源数据集
uspto-grants-2011_05
专利号
US07939302B2

关联笔记

加载中…