聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯] → 4-[(2,4-Dichlorobenzoyl)amino]-2-chlorobenzoic acid

HRID 55210

反应方程式

HRID 55210 反应方程式
[Cl:1][C:2]1[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C(N(CC)C(C)C)(C)C.[Cl:21][C:22]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:23]=1[CH2:24]Cl.[OH2:31]>C(Cl)Cl>[Cl:21][C:22]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:23]=1[C:24]([NH:11][C:9]1[CH:8]=[CH:7][C:3]([C:4]([OH:6])=[O:5])=[C:2]([Cl:1])[CH:10]=1)=[O:31]

参与物

6

反应物 4

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]HCID 72122,4-二氯氯苄HCID 171544-氨基-2-氯苯甲酸HCID 81531N,N-二异丙基乙胺

产物 1

HCID 218369754-[(2,4-Dichlorobenzoyl)amino]-2-chlorobenzoic acid

试剂、催化剂与溶剂 1

HCID 6344二氯甲烷溶剂

实验过程

To a stirred mixture of 5.19 g of 2-chloro-4-aminobenzoic acid in 150 ml of methylene chloride is added 7.86 g of N,N-diisopropylethylamine and 12.67 g of 2,4-dichlorobenzylchloride and stirring continued for 18 hours. Water is added to the filtrate and the organic layer dried with Na2SO4 and concentrated in vacuo to give 13.68 g of the desired product, m.p. 171°-175° C.

后处理

  1. dry with materialthe organic layer dried with Na2SO4
  2. concentrationconcentrated in vacuo

来源与证据

ORD记录
ord-2c6344183756424e98f2f44acba664c9
来源数据集
uspto-grants-1997_04
专利号
US05624923

关联笔记

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