3-溴哒嗪 → 5-Methyl-2-(pyridazin-3-yl)benzoic acid

HRID 61126

反应方程式

HRID 61126 反应方程式
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2[CH:16]=NC=C[N:12]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].Br[C:18]1[N:19]=NC=C[CH:23]=1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2[N:12]=[N:19][CH:18]=[CH:23][CH:16]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

参与物

3

实验过程

The title compound was prepared following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, starting with 3-bromopyridazine. ESI-MS (m/z): 215 [M+1]+.

来源与证据

ORD记录
ord-9ad7ab46b1ac411b812e5488e0181785
来源数据集
uspto-grants-2016_09
专利号
US09440982B2

关联笔记

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