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异喹啉羧酸 → 2-(((2S,3R)-1-(Isoquinoline-1-carbonyl)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 异喹啉羧酸 | HCID 68092 | — |
| 反应物 | 2-(((2S,3R)-3-Methyl-1-(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoyl)piperidin-2-yl)methyl)isoindoline-1,3-dione | HCID 117727726 | — |
| 产物 | 2-(((2S,3R)-1-(Isoquinoline-1-carbonyl)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione | HCID 117727623 | — |
反应步骤
The title compound was prepared following the same general protocol as described for 2-(((2S,3R)-3-methyl-1-(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoyl)piperidin-2-yl)methyl)isoindoline-1,3-dione in Example A1, using isoquinoline-1-carboxylic acid. ESI-MS (m/z): 414 [M+1]+.
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US09440982B2 |
| 来源数据集 | uspto-grants-2016_09 |
| ORD ID | ord-f3c70c7d7a1046a3843c24188fb49446 |
| 来源说明 | uspto-grants-2016_09 |