DL-甘油醛 → 4-(n-Hexadecylamino)benzoyl glyceraldehyde

HRID 615063

反应方程式

HRID 615063 反应方程式
[O:1]=[CH:2][CH:3]([CH2:5][OH:6])[OH:4].Cl.[CH2:8]([NH:24][C:25]1[CH:33]=[CH:32][C:28]([C:29](Cl)=[O:30])=[CH:27][CH:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].C(Cl)(Cl)Cl>CN(C)C1C=CN=CC=1.O>[CH2:8]([NH:24][C:25]1[CH:33]=[CH:32][C:28]([C:29]([C:2]([CH:3]([CH2:5][OH:6])[OH:4])=[O:1])=[O:30])=[CH:27][CH:26]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

参与物

6

反应物 3

HCID 751DL-甘油醛HCID 6212三氯甲烷HCID 132553224-Hexadecylaminobenzoyl chloride hydrochloride

产物 1

HCID 213269534-(n-Hexadecylamino)benzoyl glyceraldehyde

试剂、催化剂与溶剂 2

HCID 142844-二甲氨基吡啶(DMAP)催化剂HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂

实验过程

To a mixture of 3.6 g. of glyceraldehyde and 2.44 g. of 4-dimethylaminopyridine in an ice-bath is added 4.16 g. of 4-(n-hexadecylamino)benzoyl chloride hydrochloride. After 4 hours at room temperature, chloroform and water are added. The chloroform extract is chromatographed quickly and evaporated in vacuo to yield 4-(n-hexadecylamino)benzoyl glyceraldehyde.

后处理

  1. additionTo a mixture of 3.6 g
  2. extractionThe chloroform extract
  3. customis chromatographed quickly
  4. customevaporated in vacuo

来源与证据

ORD记录
ord-66fef1a1db6948c9940bcde96e59a27b
来源数据集
uspto-grants-1979_03
专利号
US04146546

关联笔记

加载中…