2-甲基-2-丙烯酸的均聚物 → 4-(N-2-hydroxyethyl-N-ethylamino)-4'-nitro-1,4-diphenyl-1,3-butadiene

HRID 6199

反应方程式

HRID 6199 反应方程式
[OH:1][CH2:2][CH2:3][N:4](C1C=CC(C=CC=O)=CC=1)[CH2:5][CH3:6].N[C:18]1C=CC=CC=1.[C:24]1([CH3:34])[C:25](S(O)(=O)=O)=[CH:26][CH:27]=[CH:28][CH:29]=1.C(O)(=O)C(C)=C.[N+:41]([C:44]1[CH:49]=[CH:48][C:47]([CH2:50][C:51](O)=O)=[CH:46][CH:45]=1)([O-:43])=[O:42]>C1(C)C=CC=CC=1.O>[OH:1][CH2:2][CH2:3][N:4]([C:50]([C:47]1[CH:46]=[CH:45][C:44]([N+:41]([O-:43])=[O:42])=[CH:49][CH:48]=1)=[CH:51][CH:18]=[CH:34][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1)[CH2:5][CH3:6]

参与物

8

反应物 5

HCID 40932-甲基-2-丙烯酸的均聚物HCID 4661对硝基苯乙酸HCID 6115苯胺HCID 69252-甲基苯磺酸HCID 544515964-(N-2-hydroxyethyl-N-ethylamino)cinnamaldehyde

产物 1

HCID 544465724-(N-2-hydroxyethyl-N-ethylamino)-4'-nitro-1,4-diphenyl-1,3-butadiene

试剂、催化剂与溶剂 2

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂HCID 1140甲苯溶剂

实验过程

A solution of 21.9 g (0.1 mole) of 4-(N-2-hydroxyethyl-N-ethylamino)cinnamaldehyde, 9.3 g (1 mole) of aniline, and 0.19 g (1 mole %) of toluenesulfonic acid in toluene is heated at reflux for 17 hours with azeotropic removal of water. After the mixture is cooled to room temperature, 17.2 g (0.2 mole) of methacrylic acid and 18.1 g (0.1 mole) of 4-nitrophenylacetic acid are added to the solution, and the reaction is stirred at room temperature for 3 hours. The mixture then is heated at reflux for 16 hours. After cooling to room temperature, the solid diphenylbutadiene precipitates from solution and is collected by filtration and purified by recrystallization from ethanol.

后处理

  1. temperatureThe mixture then is heated
  2. temperatureat reflux for 16 hours
  3. temperatureAfter cooling to room temperature
  4. customthe solid diphenylbutadiene precipitates from solution
  5. filtrationis collected by filtration
  6. custompurified by recrystallization from ethanol

来源与证据

ORD记录
ord-a7fdbb7f8cd94053be30d2daa540915e
来源数据集
uspto-grants-1993_09
专利号
US05247042

关联笔记

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