N-(4-甲氧基苄基)-N-甲胺 → 7-((4-methoxybenzyl)(methyl)amino)-3-(5-amino-2,4-difluorophenyl)-1-methyl-1,6-naphthyridin-2(1H)-one

HRID 687247

反应方程式

HRID 687247 反应方程式
[CH3:23][O:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][NH:30][CH3:31])[cH:32][cH:33]1.[NH2:1][c:2]1[c:3]([F:22])[cH:4][c:5]([F:21])[c:6](-[c:8]2[c:9](=[O:20])[n:10]([CH3:19])[c:11]3[cH:12][c:13]([Cl:18])[n:14][cH:15][c:16]3[cH:17]2)[cH:7]1>>[NH2:1][c:2]1[c:3]([F:22])[cH:4][c:5]([F:21])[c:6](-[c:8]2[c:9](=[O:20])[n:10]([CH3:19])[c:11]3[cH:12][c:13]([N:30]([CH2:29][c:28]4[cH:27][cH:26][c:25]([O:24][CH3:23])[cH:33][cH:32]4)[CH3:31])[n:14][cH:15][c:16]3[cH:17]2)[cH:7]1

参与物

3

反应物 2

HCID 485407N-(4-甲氧基苄基)-N-甲胺HCID 866201583-(5-Amino-2,4-difluorophenyl)-7-chloro-1-methyl-1,6-naphthyridin-2(1H)-one

产物 1

HCID 690964967-((4-methoxybenzyl)(methyl)amino)-3-(5-amino-2,4-difluorophenyl)-1-methyl-1,6-naphthyridin-2(1H)-one

来源与证据

ORD记录
ord-e6126eb499ce41899d2fd2ee5953abc0
来源数据集
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

关联笔记

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