DL-2-氨基丁酸 → N-乙酰基-DL-2-氨基-N-丁酸

HRID 7535

反应方程式

HRID 7535 反应方程式
[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>C(O)(=O)C>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

参与物

4

反应物 2

HCID 6657DL-2-氨基丁酸HCID 7918乙酐

产物 1

HCID 306107N-乙酰基-DL-2-氨基-N-丁酸

试剂、催化剂与溶剂 1

HCID 176醋酸溶剂

反应条件

温度
100 °C

实验过程

163 g (1.58 mol) 2-aminobutanoic acid are dissolved in acetic acid, and 242 g (2.37 mol) acetic anhydride are added dropwise. The mixture is stirred for 2 h at 100° C. until completion of reaction, then the solution evaporated to dryness in vacuo. The solid residue is suspended in ethyl acetate, filtered and washed with diethyl ether.

后处理

  1. customthe solution evaporated to dryness in vacuo
  2. filtrationfiltered
  3. washwashed with diethyl ether

来源与证据

ORD记录
ord-4825907718a34102b76de664069c39ba
来源数据集
uspto-grants-2006_08
专利号
US07087605B2

关联笔记

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