N,N-二甲基甲酰胺 → N-{3-[1-(6-Amino-pyrimidin-4-yl)-1H-benzoimidazol-2-ylamino]-4-methyl-phenyl}-3-morpholin-4-yl-5-trifluoromethyl-benzamide

HRID 87128

反应方程式

[CH:45]([N:46]([CH2:47][CH3:48])[CH:49]([CH3:50])[CH3:51])([CH3:52])[CH3:53].[NH2:1][c:2]1[cH:3][c:4](-[n:8]2[c:9]([NH:17][c:18]3[cH:19][c:20]([NH2:25])[cH:21][cH:22][c:23]3[CH3:24])[n:10][c:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:5][cH:6][n:7]1.[O:26]1[CH2:27][CH2:28][N:29]([c:32]2[cH:33][c:34]([C:35](=[O:36])[OH:37])[cH:38][c:39]([C:41]([F:42])([F:43])[F:44])[cH:40]2)[CH2:30][CH2:31]1.[O:78]=[CH:79][N:80]([CH3:81])[CH3:82].[P-:54]([F:55])([F:56])([F:57])([F:58])([F:59])[F:60].[n:61]1([O:62][C:63]([N:64]([CH3:65])[CH3:66])=[N+:67]([CH3:68])[CH3:69])[c:70]2[n:71][cH:72][cH:73][cH:74][c:75]2[n:76][n:77]1>>[NH2:1][c:2]1[cH:3][c:4](-[n:8]2[c:9]([NH:17][c:18]3[cH:19][c:20]([NH:25][C:35]([c:34]4[cH:33][c:32]([N:29]5[CH2:28][CH2:27][O:26][CH2:31][CH2:30]5)[cH:40][c:39]([C:41]([F:42])([F:43])[F:44])[cH:38]4)=[O:36])[cH:21][cH:22][c:23]3[CH3:24])[n:10][c:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:5][cH:6][n:7]1