聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯] → N-(4-Bromo-2,6-dimethyl-phenyl)-3,3-dimethyl-butanamide

HRID 880675

反应方程式

HRID 880675 反应方程式
[CH3:1][C:2]([CH3:8])([CH3:7])[CH2:3][C:4](Cl)=[O:5].C(N(CC)CC)C.[Br:16][C:17]1[CH:22]=[C:21]([CH3:23])[C:20]([NH2:24])=[C:19]([CH3:25])[CH:18]=1.O>C(#N)C>[Br:16][C:17]1[CH:22]=[C:21]([CH3:23])[C:20]([NH:24][C:4](=[O:5])[CH2:3][C:2]([CH3:8])([CH3:7])[CH3:1])=[C:19]([CH3:25])[CH:18]=1

参与物

6

反应物 4

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]HCID 8471三乙胺HCID 815143,3-二甲基丁酰氯HCID 905494-溴-2,6-二甲基苯胺

产物 1

HCID 59741059N-(4-Bromo-2,6-dimethyl-phenyl)-3,3-dimethyl-butanamide收率 100.1%

试剂、催化剂与溶剂 1

HCID 6342乙腈溶剂

实验过程

3,3-Dimethylbutanoyl chloride (3.37 g, 3.5 mL, 25 mmol) and triethylamine (2.53 g, 3.5 mL, 25 mmol) were added to a solution of 4-bromo-2,6-dimethylphenylamine (5.0 g, 25 mmol) in acetonitrile (30 mL). The reaction mixture was stirred at room temperature for 4 hours. Water was added to the mixture, and the precipitate which formed was collected to give the title compound as a powder (7.46 g, 100% yield).

后处理

  1. customthe precipitate which formed
  2. customwas collected

来源与证据

ORD记录
ord-e6ba9c488a0c45f598bb6beaa31a5efb
来源数据集
uspto-grants-2015_03
专利号
US08993593B2

关联笔记

加载中…