二甲胺 → Dimethyl-[(2-methyl-1H-indol-3-yl)-o-tolyl-methyl]-amine

HRID 9066

反应方程式

HRID 9066 反应方程式
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[Cl-].[CH3:12][C:13]1[CH:22]=[CH:21][CH:20]=[CH:19][C:14]=1[CH:15]=[N+:16]([CH3:18])[CH3:17].CC1C=CC=CC=1C=O.CNC>>[CH3:17][N:16]([CH3:18])[CH:15]([C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3][C:2]=1[CH3:1])[C:14]1[CH:19]=[CH:20][CH:21]=[CH:22][C:13]=1[CH3:12]

参与物

5

反应物 4

HCID 674二甲胺HCID 72242-甲基吲哚HCID 107222-甲基苯甲醛HCID 21985341(2-Methyl-benzylidene)-dimethylammonium chloride

产物 1

HCID 21985289Dimethyl-[(2-methyl-1H-indol-3-yl)-o-tolyl-methyl]-amine

实验过程

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (2-methyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-methyl-benzaldehyde and dimethylamine.

来源与证据

ORD记录
ord-d2e25ad230874e0884226fde176b5733
来源数据集
uspto-grants-2006_08
专利号
US07091220B2

关联笔记

加载中…