二甲胺 → Dimethyl-[(2-methyl-1H-indol-3-yl)-p-tolyl-methyl]-amine

HRID 9071

反应方程式

HRID 9071 反应方程式
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[Cl-].[CH3:12][C:13]1[CH:22]=[CH:21][C:16]([CH:17]=[N+:18]([CH3:20])[CH3:19])=[CH:15][CH:14]=1.CC1C=CC(C=O)=CC=1.CNC>>[CH3:19][N:18]([CH3:20])[CH:17]([C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3][C:2]=1[CH3:1])[C:16]1[CH:21]=[CH:22][C:13]([CH3:12])=[CH:14][CH:15]=1

参与物

5

反应物 4

HCID 674二甲胺HCID 72242-甲基吲哚HCID 7725对甲基苯甲醛HCID 13930190N,N-Dimethyl(4-methylphenyl)methaniminium chloride

产物 1

HCID 21985344Dimethyl-[(2-methyl-1H-indol-3-yl)-p-tolyl-methyl]-amine

实验过程

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (4-methyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 4-methyl-benzaldehyde and dimethylamine.

来源与证据

ORD记录
ord-64ec4af69c6f479089ad40c47495e9de
来源数据集
uspto-grants-2006_08
专利号
US07091220B2

关联笔记

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