聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯] → chloromaleic acid N-[2-(2-methoxyphenyl)-ethyl]-imide

HRID 979228

反应方程式

HRID 979228 反应方程式
[Cl:1][C:2]1[C:3]([O:5][C:6](=[O:8])[CH:7]=1)=[O:4].[CH3:9][O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH2:17][CH2:18][NH2:19].O>C(O)(=O)C>[CH3:9][O:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH2:17][CH2:18][N:19]=[C:3]([OH:4])/[C:2](/[Cl:1])=[CH:7]\[C:6]([OH:5])=[O:8]

参与物

5

反应物 3

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]HCID 66772CHLOROMALEIC ACID ANHYDRIDEHCID 748962-Methoxyphenethylamine

产物 1

HCID 178489456chloromaleic acid N-[2-(2-methoxyphenyl)-ethyl]-imide收率 78%

试剂、催化剂与溶剂 1

HCID 176醋酸溶剂

实验过程

13.25 g (0.1 mol) of chloromaleic anhydride and 15.2 g (0.1 mol) of 2-(2-methoxyphenyl)-ethylamine are heated to the boiling point in 100 ml of glacial acetic acid for 4 hours. 100 ml of water are then added and the oil which has precipitated is extracted with methylene chloride. The methylene chloride phase is separated off, washed with water, dried and evaporated. The oil which remains crystallizes. 20.8 g (78% of theory) of chloromaleic acid N-[2-(2-methoxyphenyl)-ethyl]-imide are obtained.

后处理

  1. customthe oil which has precipitated
  2. extractionis extracted with methylene chloride
  3. customThe methylene chloride phase is separated off
  4. washwashed with water
  5. customdried
  6. customevaporated
  7. customThe oil which remains crystallizes

来源与证据

ORD记录
ord-33887f723c6e4b00a2adcfa2a364aa5b
来源数据集
uspto-grants-1987_05
专利号
US04666935

关联笔记

加载中…