N,N-Dimethylaminoethyl chloride hydrochloride

Beige hygroscopic crystals; [Sigma-Aldrich MSDS]

Danger

H301 (69.6%): Toxic if swallowed [Danger Acute toxicity, oral]；H302 (31.6%): Harmful if swallowed [Warning Acute toxicity, oral]；H311 (74.7%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H315 (69.6%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (69.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (67.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H341 (30.4%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]；H373 (24.1%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]；H411 (31.6%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 79 reports by companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Status: Active Update: 19-06-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/8275；Status: Active Update: 31-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12032

2-Chloroethyldimethylammonium chloride: Does not have an individual approval but may be used under an appropriate group standard

A moderate skin and eye irritant; Causes somnolence, ataxia, and tremor in oral lethal-dose studies of rats; Causes diffuse hepatitis in 7-day intermittent oral studies of rats; [RTECS] A skin and strong eye irritant; Toxic by ingestion and skin absorption; [Sigma-Aldrich MSDS] See 1-Chloro-2-(diethylamine)ethane hydrochloride.

Acute Tox. 3 (69.6%)；Acute Tox. 4 (31.6%)；Acute Tox. 3 (74.7%)；Skin Irrit. 2 (69.6%)；Eye Irrit. 2 (69.6%)；STOT SE 3 (67.1%)；Muta. 2 (30.4%)；STOT RE 2 (24.1%)；Aquatic Chronic 2 (31.6%)

0.71 [mg/m3]

7.9 [mg/m3]

47 [mg/m3]

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Status: Active Update: 19-06-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/8275；Status: Active Update: 31-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12032

2-Chloroethyldimethylammonium chloride: Does not have an individual approval but may be used under an appropriate group standard

Used as an intermediate in chemical manufacture; [ExPub: ECHA REACH Registrations]

Ethanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:1): ACTIVE