4-Hydroxybenzaldehyde

1.35

1.35

-0.96

8450

8.45 mg/mL at 25 °C

slightly soluble in water; soluble in organic solvents

freely soluble (in ethanol)

310

310.00 to 311.00 °C. @ 760.00 mm Hg

117

117 °C

Dry Powder

Solid; Sublimes at atmospheric pressure without decomposition; [Merck Index] Light brown crystalline solid; [Aldrich MSDS]

Solid

Beige powder; vanillic/nutty odour

Positive

1.13

2.7

Agilent XCT

Electrospray ionization

formic acid (5.3nM)

7.61 (at 25 °C)

1311；1317；1308；1318；1324；1318.6；1320.8；1320；1302；1318；1320；1323；1320；1313.5

2958

122.34 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

118.2 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

121.6 Ų [M-H]-

Not Classified；Reported as not meeting GHS hazard criteria by 1430 of 1647 companies

Aggregated GHS information provided per 1647 reports by companies from 13 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 1430 of 1647 reports by companies.；There are 12 notifications provided by 217 of 1647 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: Benzaldehyde, 4-hydroxy-

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Benzaldehyde, 4-hydroxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzaldehyde, 4-hydroxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/26915；Status: Active Update: 13-09-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/18740

4-Hydroxybenzaldehyde: Does not have an individual approval but may be used under an appropriate group standard

Evaluation - Chemicals that are unlikely to require further regulation to manage risks to environment

Safe when used as a flavoring agent in food; [JECFA] A skin and strong eye irritant; [Aldrich MSDS]

Not Classified

Chemical: Benzaldehyde, 4-hydroxy-

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Benzaldehyde, 4-hydroxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzaldehyde, 4-hydroxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/26915；Status: Active Update: 13-09-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/18740

4-Hydroxybenzaldehyde: Does not have an individual approval but may be used under an appropriate group standard

Present in many plants in small amounts; [Merck Index] Used as flavoring agent or adjuvant; [FDA] Used to make pharmaceuticals; [Hawley]

2023: 87,300 lb；2022: 31,800 lb；2021: 71,400 lb；2020: 63,500 lb

Intermediate

Fragrance Ingredients

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

All Other Basic Organic Chemical Manufacturing

Benzaldehyde, 4-hydroxy-: ACTIVE