4-Chloro-N-methylpicolinamide 分子结构式
HCID1476814

4-Chloro-N-methylpicolinamide

4-chloro-N-methylpyridine-2-carboxamide

C7H7ClN2O170.59 g/molCAS 220000-87-3

IDENTITY

结构与身份

标准SMILES
CNC(=O)c1cc(Cl)ccn1
InChIKey
BGVBBMZMEKXUTR-UHFFFAOYSA-N
分子式
C7H7ClN2O
平均分子量
170.59 g/mol
单同位素质量
170.0246905

COMPUTED

结构计算性质

已同步
XLogP
1.1
极性表面积
42 Ų
氢键供体
1
氢键受体
2
可旋转键
1
重原子
11
形式电荷
0
复杂度
151

GHS

GHS分类

来源:PubChem
GHS Classification

Warning

H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (25%): Harmful in contact with skin [Warning Acute toxicity, dermal];H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (25%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (87.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 8 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Hazard Classes and Categories

Acute Tox. 4 (25%);Acute Tox. 4 (25%);Skin Irrit. 2 (100%);Eye Irrit. 2A (100%);Acute Tox. 4 (25%);STOT SE 3 (87.5%)

ALIASES

名称与别名

共 58 条
220000-87-34-Chloro-N-methylpicolinamide4-Chloro-N-methylpyridine-2-carboxamideDTXSID80363105RefChem:521896DTXCID80314152606-888-1N-Methyl-4-chloropyridine-2-carboxamide4-Chloro-N-methyl-2-pyridinecarboxamideMFCD02185921N-METHYL 4-CHLOROPICOLINAMIDECHEMBL41635074-Chloro-N-methylpyridine-2-carboxamide (>90%)(4-chloro(2-pyridyl))-N-methylcarboxamide4-Chloranyl-~{n}-Methyl-Pyridine-2-Carboxamide4-Chloro-N-methylpyridine-2-carboxamide (>90per cent)2-Pyridinecarboxamide, 4-chloro-N-methyl-7MU4-CHLOROPYRIDINE-2-CARBOXYLIC ACID METHYLAMIDESorafenib Impurity 47

REACTIONS

参与反应

182
HRID 13440 反应方程式

uspto-grants-2010_06 · 10.6084/m9.figshare.5104873.v1 · US07728010B2

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HRID 13444 反应方程式

uspto-grants-2010_06 · 10.6084/m9.figshare.5104873.v1 · US07728010B2

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HRID 13445 反应方程式

uspto-grants-2010_06 · 10.6084/m9.figshare.5104873.v1 · US07728010B2

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HRID 13457 反应方程式

uspto-grants-2010_06 · 10.6084/m9.figshare.5104873.v1 · US07728010B2

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HRID 78297 反应方程式

uspto-grants-2014_09 · 10.6084/m9.figshare.5104873.v1 · US08841330B2

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HRID 78298 反应方程式

uspto-grants-2014_09 · 10.6084/m9.figshare.5104873.v1 · US08841330B2

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HRID 78299 反应方程式

uspto-grants-2014_09 · 10.6084/m9.figshare.5104873.v1 · US08841330B2

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HRID 78300 反应方程式

uspto-grants-2014_09 · 10.6084/m9.figshare.5104873.v1 · US08841330B2

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