HCID1646

Tramiprosate

3-aminopropane-1-sulfonic acid

C3H9NO3S139.18 g/molCAS 3687-18-1

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IDENTITY

结构与身份

标准SMILES: NCCCS(=O)(=O)O
InChIKey: SNKZJIOFVMKAOJ-UHFFFAOYSA-N
分子式: C3H9NO3S
平均分子量: 139.18 g/mol
单同位素质量: 139.03031432

COMPUTED

结构计算性质

已同步

XLogP: -3.8
极性表面积: 88.8 Å²
氢键供体: 2
氢键受体: 4
可旋转键: 3
重原子: 8
形式电荷: 0
复杂度: 133

PROPERTIES

实验与物化性质

Solubility

<0.3 [ug/mL] (The mean of the results at pH 7.4)

GHS

GHS分类

GHS Classification

This chemical does not meet GHS hazard criteria for 10.9% (6 of 55) of reports.

Warning

H315 (89.1%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (89.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (87.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 55 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 6 of 55 reports by companies.；There are 7 notifications provided by 49 of 55 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

Regulatory Information

Status: Active Update: 13-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/11638；Status: Active Update: 13-12-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/8247

1-Propanesulfonic acid, 3-amino-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and Categories

Skin Irrit. 2 (89.1%)；Eye Irrit. 2A (89.1%)；STOT SE 3 (87.3%)

REGULATORY

法规信息

Regulatory Information

PHARMACOLOGY

药理信息

MeSH Pharmacological Classification

Drugs used to prevent SEIZURES or reduce their severity.

Endogenous compounds and drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA).

USES

用途与制造

Use Classification

Cosmetics -> Surfactant; Hydrotrope

ALIASES

名称与别名

共 122 条

TramiprosateHomotaurine3687-18-13-aminopropanesulphonic acid1-Propanesulfonic acid, 3-amino-Alzhemed3APS3-aminopropanesulfonic acid3-Aminopropane sulfonic acid3-aminopropylsulfonic acid3-APSNC-531TramiprosatoNSC-770715K8EAX0G53DTXSID80190352tramiprosatumLU-02659NC531 cpdRefChem:898661

REACTIONS