结构:CC(=O)Oc1ccccc1C(=O)[O-].CC(=O)Oc1ccccc1C(=O)[O-].NC(N)=O.[Ca+2]
HCID21975

Carbaspirin Calcium

calcium;bis(2-acetyloxybenzoate);urea

C19H18CaN2O9458.4 g/molCAS 5749-67-7

IDENTITY

结构与身份

标准 SMILES
CC(=O)Oc1ccccc1C(=O)[O-].CC(=O)Oc1ccccc1C(=O)[O-].NC(N)=O.[Ca+2]
InChIKey
VYMUGTALCSPLDM-UHFFFAOYSA-L
分子式
C19H18CaN2O9
平均分子量
458.4 g/mol
单同位素质量
458.063821

COMPUTED

结构计算性质

已同步
极性表面积
202 Ų
氢键供体
2
氢键受体
9
可旋转键
4
重原子
31
形式电荷
0
复杂度
235

GHS

GHS 分类

来源:PubChem
GHS Classification

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation];H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Hazard Classes and Categories

Acute Tox. 4 (100%)

PHARMACOLOGY

药理信息

来源:PubChem
ATC Code

N - Nervous system;N02 - Analgesics;N02B - Other analgesics and antipyretics;N02BA - Salicylic acid and derivatives;N02BA15 - Carbasalate calcium

B - Blood and blood forming organs;B01 - Antithrombotic agents;B01A - Antithrombotic agents;B01AC - Platelet aggregation inhibitors excl. heparin;B01AC08 - Carbasalate calcium

QN - Nervous system;QN02 - Analgesics;QN02B - Other analgesics and antipyretics;QN02BA - Salicylic acid and derivatives;QN02BA15 - Carbasalate calcium

QB - Blood and blood forming organs;QB01 - Antithrombotic agents;QB01A - Antithrombotic agents;QB01AC - Platelet aggregation inhibitors, excl. heparin;QB01AC08 - Carbasalate calcium

MeSH Pharmacological Classification

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

ALIASES

名称与别名

59
CARBASPIRIN CALCIUMCalcium carbaspirinN667F17JP1DTXSID90206099carbosalate calciumCalcium carbasalateCalcium acetylsalicylic carbamidateRefChem:574158DTXCID40128590calcium urea bis(2-(acetyloxy)benzoate)227-273-0Carbasalate calcium5749-67-7Carbasalate calciqueCarbasalato calcicoCarbaspirin calcium [USAN]Carbasalate calcium [INN]calcium;2-acetyloxybenzoate;ureaCarbasalate calcium (INN)Carbaspirin calcium (USAN)

REACTIONS

参与反应

0

当前筛选下没有反应记录。