Feprazone
Basic information
- CAS
30748-29-9- Standard SMILES
CC(C)=CCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O- InChIKey
RBBWCVQDXDFISW-UHFFFAOYSA-N- Molecular formula
- C20H20N2O2
- Average molar mass
- 320.4 g/mol
- Monoisotopic mass
- 320.15247789
Overview
Feprazone is an organic molecular entity.
Names & identifiers
- Preferred name
- Feprazone
- IUPAC
- 4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione
- English name
- Feprazone
- Molecular formula
- C20H20N2O2
- Molecular weight
- 320.39
Names & synonyms
Feprazone30748-29-9PrenazoneFenilprenazonePhenylprenazoneFeprazonaDA 2370FeprazonumDA-2370DTXSID30230514-(3-Methyl-2-butenyl)-1,2-diphenyl-3,5-pyrazolidinedione7BVX6J0CGR
Show more names
analudZepelinGrisonaNalovenNilatinTabrienpheprazone
4-(3-methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dioneDTXCID203051RefChem:598945M01AX18M02AA16DA2370250-324-3Methrazone
Database identifiers
- CAS
30748-29-9- PubChem CID
- 35455
- DTXSID
DTXSID3023051- ChEMBL
CHEMBL1452696- ChEBI
CHEBI:31603- UNII
- 7BVX6J0CGR
- EC Number
- 250-324-3
- Nikkaji
- J3.175E
Properties
Computed structural properties
- XLogP
- 3.1
- Topological polar surface area
- 40.6 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 4
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 462
Physicochemical properties
- Melting point
- 156.5 ° · 156.5° (ethanol)
- Boiling point
- 459.28 °C · 459.28°C (rough estimate)
- Density
- 1.167 · 1.1670 (rough estimate)
- refractive index
- 1.57 · 1.5700 (estimate)
- storage temp.
- -20 °C · -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 5.09 · 5.09 ± 0.07(at 25℃)
- form
- Solid
- color
- Pale Yellow to Yellow
- InChI
- InChI=1S/C20H20N2O2/c1-15(2)13-14-18-19(23)21(16-9-5-3-6-10-16)22(20(18)24)17-11-7-4-8-12-17/h3-13,18H,14H2,1-2H3
- InChIKey
- RBBWCVQDXDFISW-UHFFFAOYSA-N
- SMILES
- N1(C2=CC=CC=C2)C(=O)C(C/C=C(/C)\C)C(=O)N1C1=CC=CC=C1
- CAS DataBase Reference
- 30748 · 30748-29-9(CAS DataBase Reference)
- FDA UNII
- 7 BVX6J0CGR · 7BVX6J0CGR
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Other Safety InformationIMAP assessments - 3,5-Pyrazolidinedione, 4-(3-methyl-2-butenyl)-1,2-diphenyl-: Environment tier I assessment
Safety data
- Toxicity
- LD50 in male mice, rats (mg/kg): 408.8, 386.4 i.p.; 1067, >2000 orally (Bianchi, Bonardi)
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Chemistry & industry
Pharmacology
ATC Code
M - Musculo-skeletal system
M - Musculo-skeletal system
QM - Musculo-skeletal system
QM - Musculo-skeletal system
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Applications
UsesFeprazone is a anti-inflammatory agent used in the management of inflammatory or degenerative joint diseases.
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionChEBI: Feprazone is an organic molecular entity.
Related reactions
3 records
Compound notes
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