붕소

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

1.9 [mg/m3]

21 [mg/m3]

130 [mg/m3]

Limit for livestock is 5 ug/mL boron in water. /Boron/

0.5 mg/L maximum (USSR) /Boron in drinking water/

Developmental (effects during periods when organs are developing), Hematological (Blood Forming), Hematological (Blood Forming), Reproductive (Producing Children), Respiratory (From the Nose to the Lungs)

Developmental

IDENTIFICATION: (Elemental boron exists as a solid at room temperature, either as black monoclinic crystals or as a yellow or brown amorphous powder when impure). It is a naturally occurring element that is found in the form of borates in the oceans, sedimentary rocks, coal, shale, and some soils. Boron enters the environment mainly through the weathering of rocks, boric acid volatilization from seawater, and volcanic activity. Boron is also released from anthropogenic sources to a lesser extent. These sources include agricultural, refuse, and fuel wood burning, power generation using coal and oil, glass product manufacture, use of borates/perborates in the home and industry, borate mining/processing, leaching of treated wood/paper, and sewage/sludge disposal. HUMAN EXPOSURE: Only a few human studies have been conducted to assess health effects associated with exposure to boron compounds. The available data show that exposure is associated with short-term irritant effects on the upper respiratory tract, nasopharynx, and eye. These effects, however, appear to be short-term and reversible. The sole long-term (7-year) follow-up study failed to identify any long-term health effects. No studies have been identified that assess reproductive outcomes. Based on the lack of human data and the limited animal data, boron is not classifiable as to its human carcinogenicity. ANIMAL STUDIES: Data regarding developmental and reproductive toxicity show that lower fetal body weight in rats is the critical effect. As dose level increases, the effects seen include: further rib effects and testicular pathology in the rat, decreased fetal body weight and increased fetal cardiovascular malformations in the rabbit, and severe testicular pathology in the rat; testicular atrophy and sterility in the rat; reduced fetal body weight in the mouse. Animal studies on mice and rats showed no evidence of carcinogenicity of boric acid. /Boron and Boron compounds/

Boron and Compounds

Developmental

2 x 10 ^-1 mg/kg-day

The use and production of boron and boron compounds in products such as fiberglass, soaps, detergents, enamels, frits, glazes, and fire retardants, and their use in industries such as agriculture, metallurgy, chemical synthesis, and in nuclear applications(1-5) may result in their release to the environment through various waste streams(SRC).

/LABORATORY ANIMALS: Subchronic or Prechronic Exposure/ ... 15 mice ... /were/ exposed on an inhalation schedule of /amorphous boron/ 7 hr/day, 5 days/wk, for 30 days. Exposure levels averaged 72.8 mg/cu m with a wide standard deviation of 42.4. Median particle size was 0.67 micrometer, standard deviation 2.0. Under these exposure conditions there was scant evidence of toxicologic effects ... Mean weight loss of 7% during the first wk was later recovered in steady increases ...

Basic treatment: Establish a patent airway. Suction if necessary. Aggressive airway management may be necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressing after decontamination ... . /Boron and Related Compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Early intubation at the first sign of upper airway obstruction may be necessary. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . Consider vasopressors to treat hypotension without signs of hypovolemia ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Boron and related compounds/

Maintain an open airway and assist ventilation if nescessary. treat coma, seizures, hypotension, and renal failure if they occur. There is no specific antidote. Administer activated charcoal (although boric acid is not well absorbed). Consider gastric lavage for large ingestions. /Boric acid, Borates, and Boron/

Hemodialysis is effective and is indicated after massive ingestions and for supportive care of renal failure. Peritoneal dialysishas not proved effective in enhancing elimination in infants. /Boric acid, Borates, and Boron/

For more Antidote and Emergency Treatment (Complete) data for BORON, ELEMENTAL (7 total), please visit the HSDB record page.

Chemical: Boron

Hazard Traits - Developmental Toxicity; Environmental tox；Authoritative List - CA NLs; CWA 303(d)；Report - if used as a fragrance or flavor ingredient

Boron is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Boron are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 31-01-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14776

Boron: Does not have an individual approval but may be used under an appropriate group standard

(CA) CALIFORNIA 1000 ug/L

(NH) NEW HAMPSHIRE 630 ug/L

(ME) MAINE 1,400 ug/L

(MN) MINNESOTA 1,000 ug/L

(WI) WISCONSIN 960 ug/L