结构:FC(F)(Br)Br
HCID6382

Dibromodifluoromethane

dibromo(difluoro)methane

CBr2F2209.82 g/molCAS 75-61-6

IDENTITY

结构与身份

标准 SMILES
FC(F)(Br)Br
InChIKey
AZSZCFSOHXEJQE-UHFFFAOYSA-N
分子式
CBr2F2
平均分子量
209.82 g/mol
单同位素质量
207.83348

COMPUTED

结构计算性质

已同步
XLogP
2.6
极性表面积
0 Ų
氢键供体
0
氢键受体
2
可旋转键
0
重原子
5
形式电荷
0
复杂度
30

PROPERTIES

实验与物化性质

来源:PubChem
LogP

1.99

Odor

Characteristic odor

Density

2.29 at 59 °F (NIOSH, 2024) - Denser than water; will sink

2.3063 g/cu cm @ 15 °C

Density (gas): 8.7 kg/m³

2.29 at 59 °

(59 °F): 2.29

Color/Form

Colorless heavy liq

COLORLESS GAS

Colorless, heavy liquid or gas (above 76 degrees F).

Solubility

Insoluble (NIOSH, 2024)

Sol in ether, acetone, benzene, and water.

Sol in methanol; insol in water

Solubility in water: none

Insoluble

Boiling Point

76 °F at 760 mmHg (NIOSH, 2024)

25 °C @ 760 mm Hg

22.8 °C

76 °F

76 °F

Decomposition

WHEN HEATED TO DECOMPOSITION, IT EMITS VERY TOXIC FUMES OF /HYDROGEN BROMIDE AND HYDROGEN FLUORIDE./

Melting Point

-231 °F (NIOSH, 2024)

-110.1 °C

-101.1 °C

-231 °F

-231 °F

Vapor Density

7.2 (AIR= 1)

Relative vapor density (air = 1): 7.2

Vapor Pressure

620 mmHg (NIOSH, 2024)

820.0 [mmHg]

820 mm Hg @ 25 °C

Vapor pressure, kPa at 20 °C: 83

620 mmHg

620 mmHg

Surface Tension

3.976X10-2 N/m @ -110 °C

Refractive Index

Index of refraction: 1.399 @ 12 °C

GHS

GHS 分类

来源:PubChem
GHS Classification

Warning

H420 (100%): Harms public health and the environment by destroying ozone in the upper atmosphere [Warning Hazardous to the ozone layer]

P502</a, and a href="https://pubchem.ncbi.nlm.nih.gov/ghs/#P502">P502 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Regulatory Information

Chemical: Methane, dibromodifluoro-

Dibromodifluoromethane: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Other Safety Information

Evaluation - Chemicals that are unlikely to require further regulation to manage risks to human health

DOT Label

Class 9

Fire Hazards

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, Capacitor, asymmetric, be aware of possible short circuiting as this product is transported in a charged state. Polymeric beads, expandable (UN2211) may evolve flammable vapours. (ERG, 2024)

· Some may burn but none ignite readily.;· Containers may explode when heated.;· Some may be transported hot.;· For UN3508, Capacitor, asymmetric, be aware of possible short circuiting as this product is transported in a charged state.;· Polymeric beads, expandable (UN2211) may evolve flammable vapours.

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Fire Potential

NONFLAMMABLE.

Health Hazards

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or asphyxiation. Runoff from fire control or dilution water may cause environmental contamination. (ERG, 2024)

· Inhalation of material may be harmful.;· Contact may cause burns to skin and eyes.;· Inhalation of Asbestos dust may have a damaging effect on the lungs.;· Fire may produce irritating, corrosive and/or toxic gases.;· Some liquids produce vapors that may cause dizziness or asphyxiation.;· Runoff from fire control or dilution water may cause environmental contamination.

Hazards Summary

Pulmonary damage is noted in animals after a single exposure of 4000 ppm. Decomposition may yield hydrogen bromide and hydrogen fluoride; TLV Basis = irritation of upper respiratory tract, liver damage, and CNS impairment; [ACGIH] See CHLOROFLUOROCARBONS.

DOT ID and Guide

1941 171

1941 171

Reactive Group

Fluorinated Organic Compounds

UN Classification

UN Hazard Class: 9; UN Pack Group: III

Reactivity Profile

DIBROMODIFLUOROMETHANE is incompatible with the following: Chemically-active metals such as sodium, potassium, calcium, powdered aluminum, zinc & magnesium (NIOSH, 2024).

Chemical Dangers

Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive gases including hydrogen bromide and hydrogen fluoride. Reacts with alkali metals, powdered aluminium, magnesium and zinc.

SAFETY

安全与防护

来源:PubChem
Fire Fighting

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;CAUTION: Fire involving Safety devices (UN3268) and Fire suppressant dispersing devices (UN3559) may have a delayed activation and a risk of hazardous projectiles. Extinguish the fire at a safe distance.;SMALL FIRE: Dry chemical, CO2, water spray or regular foam.;LARGE FIRE: Water spray, fog or regular foam. Do not scatter spilled material with high-pressure water streams. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.;FIRE INVOLVING TANKS: Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

In case of fire in the surroundings, use appropriate extinguishing media.

First Aid Measures

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Accidental Release Measures

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.;· Keep unauthorized personnel away.;· Stay upwind, uphill and/or upstream.

· Do not touch or walk through spilled material.;· Stop leak if you can do it without risk.;· Prevent dust cloud.;· For Asbestos, avoid inhalation of dust. Cover spill with plastic sheet or tarp to minimize spreading. Do not clean up or dispose of, except under supervision of a specialist.;Small Dry Spill;· With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.;Small Spill;· Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.;Large Spill;· Dike far ahead of liquid spill for later disposal.;· Cover powder spill with plastic sheet or tarp to minimize spreading.;· Prevent entry into waterways, sewers, basements or confined areas.

First Aid

Excerpt from NIOSH Pocket Guide for Difluorodibromomethane:;Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.;Skin: WATER FLUSH IMMEDIATELY - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.;Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.;Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2024)

General First Aid:;· Call 911 or emergency medical service.;· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.;· Move victim to fresh air if it can be done safely.;· Administer oxygen if breathing is difficult.;· If victim is not breathing:;-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.;-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).;-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.;· Remove and isolate contaminated clothing and shoes.;· For minor skin contact, avoid spreading material on unaffected skin.;· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.;· For severe burns, immediate medical attention is required.;· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.;· Keep victim calm and warm.;· Keep victim under observation.;· For further assistance, contact your local Poison Control Center.;· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

(General first aid procedures);Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.;Skin: Water flush immediately - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.;Breathing: Respiratory support;Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.

Safe Storage

See Chemical Dangers.

Exposure Control and Personal Protection

· Wear positive pressure self-contained breathing apparatus (SCBA).;· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

Storage Conditions

IN GENERAL, MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS ... SHOULD BE STORED IN A COOL, WELL-VENTILATED PLACE, OUT OF DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, & SHOULD BE PERIODICALLY INSPECTED ... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED FROM EACH OTHER.

Nonfire Spill Response

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent dust cloud. For Asbestos, avoid inhalation of dust. Cover spill with plastic sheet or tarp to minimize spreading. Do not clean up or dispose of, except under supervision of a specialist.;SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.;SMALL SPILL: Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.;LARGE SPILL: Dike far ahead of liquid spill for later disposal. Cover powder spill with plastic sheet or tarp to minimize spreading. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2024)

Disposal Methods

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Spillage Disposal

Ventilation. Do NOT let this chemical enter the environment.

Preventive Measures

SUFFICIENT EXHAUST & GENERAL VENTILATION SHOULD BE PROVIDED ... EXCESS SKIN CONTACT WITH LIQ FLUOROCARBONS SHOULD BE MINIMIZED TO PREVENT DEFATTING OF SKIN & POSSIBLE SKIN ABSORPTION. /FLUOROCARBONS/

If this chemical gets into the eyes, irrigate immediately. If this chemical contacts the skin, flush with water immediately. ... Remove nonimpervious clothing promptly if wet or contaminated.

FILLING AREAS SHOULD BE MONITORED TO ENSURE THAT THE AMBIENT CONCN OF FLUOROCARBONS DOES NOT EXCEED 1000 PPM ... INHALATION OF FLUOROCARBON VAPORS SHOULD BE AVOIDED ... /FLUOROCARBONS/

APPEARANCE OF TOXIC DECOMP PRODUCTS SERVES AS WARNING OF OCCURRENCE OF THERMAL DECOMP & DETECTION OF SHARP ACRID ODOR WARNS OF PRESENCE ... HALIDE LAMPS OR ELECTRONIC LEAK DETECTORS MAY ALSO BE USED. ADEQUATE VENTILATION ALSO AVOIDS PROBLEM OF TOXIC DECOMPOSITION PRODUCTS. /FLUOROCARBONS/

For more Preventive Measures (Complete) data for DIBROMODIFLUOROMETHANE (7 total), please visit the HSDB record page.

Isolation and Evacuation

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.;SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.;FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure;· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.;Spill;· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.;· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.;Fire;· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

TOXICITY

毒理信息

来源:PubChem
Interactions

IF INHALATION OCCURS, EPINEPHRINE OR OTHER SYMPATHOMIMETIC AMINES & ADRENERGIC ACTIVATORS SHOULD NOT BE ADMIN SINCE THEY WILL FURTHER SENSITIZE HEART TO DEVELOPMENT OF ARRHYTHMIAS. /FLUOROCARBONS/

Target Organs

respiratory system, central nervous system, liver

Environmental Fate

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 49(SRC), determined from a structure estimation method(2), indicates that dibromodifluoromethane is expected to have very high mobility in soil(SRC). Volatilization of dibromodifluoromethane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 0.03 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Volatilization of dibromodifluoromethane from dry soil surfaces is expected to occur rapidly(SRC) based upon a vapor pressure of 820 mm Hg(4). Based upon the highly halogenated structure of dibromodifluoromethane, biodegradation is expected to be slow(5).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 49(SRC), determined from a structure estimation method(2), indicates that dibromodifluoromethane is not expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 0.03 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 1.5 hrs and 5.7 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 6.9(SRC), from an estimated log Kow(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low. Based upon the highly halogenated structure of dibromodifluoromethane, biodegradation is expected to be slow(8).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dibromodifluoromethane, which has a vapor pressure of 820 mm Hg at 25 °C(2), is expected to exist solely in the vapor-phase in the ambient atmosphere. Vapor-phase dibromodifluoromethane is slowly degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be greater than 44 years(3), based on its rate constant of <5.0X10-16 cu cm/molecule-sec at 25 °C(4). Dibromodifluoromethane absorbs very little UV radiation above 290 nm and is not expected to photolyze at an environmentally important rate in the ambient atmosphere(5). Based on dibromodifluoromethane's long residence time in the atmosphere, it will diffuse gradually into the upper limits of the troposphere, and eventually into the stratosphere above the ozone layer where it will contribute to ozone depletion(6).

Adverse Effects

Neurotoxin - Acute solvent syndrome;Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.;Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

Exposure Routes

The substance can be absorbed into the body by inhalation.

inhalation, ingestion, skin and/or eye contact

Signs and Symptoms

Cough. Sore throat. Laboured breathing. Shortness of breath. Confusion. Drowsiness. Unconsciousness.

In Animals: irritation respiratory system; central nervous system symptoms; liver damage

ICSC Environmental Data

Avoid release to the environment because of its impact on the ozone layer.

Medical Surveillance

Consider the points of attack /skin, respiratory system/ in preplacement and periodic physical examinations.

Soil Adsorption/Mobility

Using a structure estimation method based on molecular connectivity indices(1), the Koc for dibromodifluoromethane can be estimated to be about 49(SRC). According to a classification scheme(2), this estimated Koc value suggests that dibromodifluoromethane is expected to have very high mobility in soil.

TSCA Test Submissions

Dibromodifluoromethane (CBr2F2, CAS # 75-61-6) was evaluated for behavioral changes associated with acute inhalation toxicity in 4 male cats individually exposed in an airtight Plexiglas cages to slowly increasing atmospheric concentrations (in air) approaching 3 vol%. Evaporated from a thermostated vessel, CBr2F2 was mixed immediately with the main air supply (gas density of 1.90 gm/cm3), the ambient atmospheric content controlled by floating-body gauges and monitored by gas densitometer at the exhaust end of the experimental chamber. Treatment in 2 cats each of 99.4 and 96.4 vol% samples was associated with clinical signs of increasing gravity with increasing atmospheric concentrations, including enlarged pupils and blinking eyelids, arched back, head shaking, raised fur, tremor, slight to extreme restlessness, static gait, optisthotonus, gasping, salivation, prostration and marked ataxia, tonic convulsions, and clonic convulsions. The symptoms, their time to onset and the associated atmospheric levels of CBr2F2 were largely consistent between individual cats and samples, with behavioral changes and narcosis first noted at approximately 0.5% v/v (10 minutes) and convulsions at 2.2-2.7 v/v (44-57 minutes). The time to near recovery, generally defined by the authors by the cat's return to its feet, ranged from 2.5 to 10 minutes after termination of the exposures, although ataxia persisted (duration unspecified) in all animals.

Atmospheric Concentrations

URBAN/SUBURBAN: Numerous air samples taken from four separate landfills located in New Jersey contained detectable levels of dibromodifluoromethane(1). At one landfill, dibromodifluoromethane was detected 85% of the time while at the other three landfills it was detected 65% of the time (concentrations not specified)(1). A study of the types and levels of brominated compounds released into the atmosphere by chemical manufacturers in the state of Arkansas revealed detectable levels of dibromodifluoromethane over a two year period(2). Many of the chemicals studied were detected off plant property suggesting transport into neighboring environments was occurring(2).

Human Toxicity Excerpts

EARLY ... HUMAN EXPERIENCE INDICATED THAT HIGH VAPOR CONCN (EG, 20%) MAY CAUSE CONFUSION, PULMONARY IRRITATION, TREMORS & RARELY COMA, BUT THAT THESE EFFECTS WERE GENERALLY TRANSIENT & WITHOUT LATE SEQUELAE. ... CAUSE OF DEATH /FROM ABUSE OF FLUOROCARBONS/ IS IN CONSIDERABLE DOUBT. FREEZING OF AIRWAY SOFT TISSUES CAN PROBABLY BE ELIMINATED AS A CAUSE OF DEATH EXCEPT IN CASES WHERE THE PRODUCT WAS SPRAYED DIRECTLY INTO THE MOUTH FROM ITS CONTAINER OR FROM A BALLOON CONTAINING SOME LIQUID. LARYNGEAL SPASM OR EDEMA, OXYGEN DISPLACEMENT, OR SENSITIZATION OF MYOCARDIUM TO ENDOGENOUS CATECHOLAMINES WITH SUBSEQUENT VENTRICULAR FIBRILLATION APPEAR TO BE REASONABLE POSSIBILITIES. /FLUOROCARBONS/

A SPECIAL CLASS OF CHEMICALS SUBJECT TO ABUSE BY INHALATION ARE THE FLUOROHYDROCARBONS ... THE "SNIFFING" OF SUCH AEROSOL SPRAYS IS HAZARDOUS PRACTICE. ... 110 "SUDDEN SNIFFING DEATHS" /HAVE BEEN IDENTIFIED/ ... IN EACH CASE THE VICTIM SPRAYED THE AEROSOL INTO A PLASTIC BAG, INHALED THE CONTENTS, BECAME EXCITED, RAN 90 M OR SO, COLLAPSED, & DIED. NECROPSY FINDINGS WERE LARGELY NEGATIVE ... ALTHOUGH AMOUNT OF PROPELLANT ABSORBED INTO BLOOD FROM USE OF HAIRSPRAY, COSMETIC, HOUSEHOLD, & MEDICATED AEROSOLS MUST VARY WITH CIRCUMSTANCES, PHYSICIAN IS ADVISED TO COUNSEL ... PATIENT ON POTENTIAL DANGERS, PARTICULARLY FROM THEIR USE IN POORLY VENTILATED CONFINED AREAS. IT IS POSSIBLE THAT PATIENTS WITH CARDIAC OR RESPIRATORY DISORDERS MAY PROVE ESPECIALLY SUSCEPTIBLE. /FLUOROHYDROCARBONS/

Fluorocarbons containing bromine ... are more toxic than the corresponding chloro compounds. /Fluorocarbons/

MANUFACTURING PROCESSES USE HYDROFLUORIC ACID FROM FLUOROSPAR IN PRODUCTION OF ALL FLUOROCARBONS. SOME PROCESSES USE CARBON TETRACHLORIDE FROM CARBON DISULFIDE, OR AS CO-PRODUCT OF PERCHLOROETHYLENE & CHLORINATION OF PROPYLENE, OR CHLOROFORM FROM CHLORINATION OF METHANOL. THE MAJOR HAZARDS RELATE PRIMARILY TO THE INADVERTENT RELEASE OF HYDROFLUORIC ACID OR CARBON TETRACHLORIDE, RATHER THAN TO THE MANUFACTURED FLUOROCARBONS. /FLUOROCARBONS/

FLUOROCARBON VAPORS ARE FOUR TO FIVE TIMES HEAVIER THAN AIR. THUS HIGH CONCN TEND TO ACCUMULATE IN LOW-LYING AREAS, RESULTING IN HAZARD OF INHALATION OF CONCENTRATED VAPORS, WHICH MAY BE FATAL. ... THE HIGHEST EXPOSURE IN THE PLANT OCCURS WITH VENTING OF GASES FROM RETURNABLE CYLINDERS. /FLUOROCARBONS/

REGULATORY

法规信息

来源:PubChem
Regulatory Information

Chemical: Methane, dibromodifluoro-

Dibromodifluoromethane: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

PHARMACOLOGY

药理信息

来源:PubChem
Mechanism of Action

Cardiac arrhythmia, possibly aggravated by elevated levels of catecholamines due to stress ... is suggested as the cause of these adverse responses, which may lead to death. /Fluorocarbons/

Absorption, Distribution and Excretion

... MAIN FACTOR AFFECTING FATE OF FLUOROCARBONS IS BODY FAT, WHERE THEY ARE CONCENTRATED & SLOWLY RELEASED INTO BLOOD @ CONCN THAT SHOULD NOT CAUSE ANY RISK OF CARDIAC SENSITIZATION. /FLUOROCARBONS/

THERE IS A SIGNIFICANT ACCUMULATION OF PROPELLANTS IN BRAIN, LIVER & LUNG COMPARED TO BLOOD LEVELS, SIGNIFYING PROPELLANT TISSUE DISTRIBUTION SIMILAR TO THAT OF CHLOROFORM. /FLUOROCARBONS/

USES

用途与制造

来源:PubChem
Uses

Has been used in fire extinguishers and as a chemical intermediate; [ACGIH]

See CHLOROFLUOROCARBONS

FIRE-EXTINGUISHING AGENT

Synthesis of dyes, pharmaceuticals, quarternary ammonium cmpd

POLYMER INTERMEDIATE

This and other Freons are used occasionally to trace the plume of major power plants

U.S. Production

(1977) PROBABLY GREATER THAN 2.27X10+6 G

Methods of Manufacturing

Vapor phase bromination of difluoromethane

Formulations/Preparations

Grades: Pure (95.0% minimum)

General Manufacturing Information

Methane, dibromodifluoro-: ACTIVE

MECHANICAL VAPOR COMPRESSION SYSTEMS USE FLUOROCARBONS FOR REFRIGERATION & AIR CONDITIONING & ACCOUNT FOR ... MAJORITY OF REFRIGERATION CAPABILITY IN US. ... FLUOROCARBONS ARE USED AS REFRIGERANTS IN HOME APPLIANCES, MOBILE AIR CONDITIONING UNITS, RETAIL FOOD REFRIGERATION SYSTEMS & ... CHILLERS. /FLUOROCARBONS/

THE BROMINE-CONTAINING FLUOROCARBONS OPERATE BY CHEMICAL INTERRUPTION OF THE COMBUSTION CHAIN, AND ARE USED IN TOTAL FLOODING SYSTEMS FOR COMPUTER ROOMS AND TELEPHONE FACILITIES, AS WELL AS AIRCRAFT AND PORTABLE FIRE EXTINGUISHERS, INCLUDING USE ON THE AIR FORCE P-13 RAPID INTERVENTION CRASH TRUCKS. HALON EMERGES FROM THE FIRE EXTINGUISHER NOZZLE AS A MIXTURE OF 85 PERCENT LIQUID AND 15 PERCENT VAPOR AND IS DISCHARGED OVER LONG DISTANCES. IT COMPLETELY VAPORIZES UPON CONTACT WITH FIRE. /BROMINATED FLUOROCARBONS/

ALIASES

名称与别名

49
DIBROMODIFLUOROMETHANE75-61-6DifluorodibromomethaneHalon 1202Methane, dibromodifluoro-Freon 12-B2Fluorocarbon 12-B2UN1941HSDB 1335Carbon dibromide difluorideEINECS 200-885-5R 12B2BRN 173251582022727JDDTXSID90587894-01-00-00080 (Beilstein Handbook Reference)DIFLUORODIBROMOMETHANE [HSDB]CARBON BROMIDE FLUORIDE (CBR2F2)Fluorocarbon 12B2Freon12B2

REACTIONS

参与反应

84
HRID88410

Training data from https://doi.org/10.1039/C8SC04228D (2/10)

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HRID90549

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HRID107311

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HRID119290

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