HCID72327

Fmau

1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

C10H13FN2O5260.22 g/molCAS 69256-17-3

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IDENTITY

结构与身份

标准SMILES: Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)c(=O)[nH]c1=O
InChIKey: GBBJCSTXCAQSSJ-JVZYCSMKSA-N
分子式: C10H13FN2O5
平均分子量: 260.22 g/mol
单同位素质量: 260.08084968

COMPUTED

结构计算性质

已同步

XLogP: -0.9
极性表面积: 99.1 Å²
氢键供体: 3
氢键受体: 6
可旋转键: 2
重原子: 18
形式电荷: 0
复杂度: 413

PHARMACOLOGY

药理信息

MeSH Pharmacological Classification

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

ALIASES

名称与别名

共 55 条

69256-17-3FMAUD-FMAU2'-Fluoro-5-methylarabinosyluracil5-Methyl-2'-fluoroarauracil1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracilNSC-67851637F7D05ANBJ61.760A2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-2'-deoxy-2'-fluoroarabinofuranosylthymineRefChem:1972201-(2-fluoro-2-deoxy-beta-arabinofuranosyl)thymine1-(2-fluoro-2-deoxy-beta-d-arabinofuranosyl)thymine1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione,1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dioneMFCD00870799C10H13FN2O5

REACTIONS