(-)-Tramadol Hydrochloride

(S,S)-tramadol hydrochloride is a hydrochloride resulting from the reaction of (S,S)-tramadol with 1 molar equivalent of hydrogen chloride; the (S,S)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold lower analgesic potency than the (R,R)-enantiomer. It has a role as an opioid analgesic, an adrenergic uptake inhibitor, a serotonergic antagonist, a muscarinic antagonist, a serotonin uptake inhibitor, an antitussive, a mu-opioid receptor agonist, a kappa-opioid receptor agonist, a NMDA receptor antagonist, a delta-opioid receptor agonist and a capsaicin receptor antagonist. It contains a (S,S)-tramadol(1+). It is an enantiomer of a (R,R)-tramadol hydrochloride.