β-Hydroxy-4-(2-hydroxyethyl)piperazin-1-propansulfonsure
1-Piperazinepropanesulfonic acid, beta-hydroxy-4-(2-hydroxyethyl)-
Grundinformationen
- CAS
68399-78-0- Standard-SMILES
O=S(=O)(O)CC(O)CN1CCN(CCO)CC1- InChIKey
GIZQLVPDAOBAFN-UHFFFAOYSA-N- Summenformel
- C9H20N2O5S
- Durchschnittliche Molmasse
- 268,33 g/mol
- Monoisotopische Masse
- 268,10929292
Überblick
HEPPSO is a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine.
Namen und Bezeichner
- Bevorzugter Name
- 1-Piperazinepropanesulfonic acid, beta-hydroxy-4-(2-hydroxyethyl)-
- IUPAC
- 2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
- Lokaler Name
- β-Hydroxy-4-(2-hydroxyethyl)piperazin-1-propansulfonsure
- Englischer Name
- HEPPSO
- Summenformel
- C9H20N2O5S
- Molmasse
- 268.33
Namen und Synonyme
NSC 3741131-Piperazinepropanesulfonic acid, .beta.-hydroxy-4-(2-hydroxyethyl)-EINECS 269-990-1DTXSID008873531-Piperazinepropanesulfonic acid, beta-hydroxy-4-(2-hydroxyethyl)-RefChem:435794DTXCID70872817HEPPSO68399-78-02-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid2-Hydroxy-3-(4-(2-hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acidN-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid
Weitere Namen anzeigen
beta-hyHEPPSO 99+%HEPPSO 98+%HEPPSO BufferHEPPSO HydrateHEPPSO ULTRAPUREHEPPSO, FREE ACIDHEPPSO Hydrate, >=99%LABOTEST-BB LT00138033
MFCD000383513-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-hydroxypropanesulfonic Acid2-Hydroxy-3-[4-(2-hydroxyethyl)-1-piperazinyl]propane-1-sulfonic Acidbeta-Hydroxy-4-(2-hydroxyethyl)piperazine-1-propanesulphonic acidNSC3741134-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid)beta-hydroxy-4-(2-hydroxyethyl)-1-piperazinepropanesulfonic acid4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane sulfonic acid)Free Acid
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -4,6
- Polarare Oberfläche (TPSA)
- 110 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 6
- Schwere Atome
- 17
- Formalladung
- 0
- Komplexität
- 308
Physikochemische Eigenschaften
- Schmelzpunkt
- 158 · 158-160°C
- Dichte
- 1.382 · 1.382±0.06 g/cm3(Predicted)
- Wasserlöslichkeit
- almost transparency in Water
- pka
- 1.1 · 1.10±0.50(Predicted)
- Aggregatzustand
- Liquid
- Farbe
- White to Almost white
- InChI
- InChI=1S/C9H20N2O5S/c12-6-5-10-1-3-11(4-2-10)7-9(13)8-17(14,15)16/h9,12-13H,1-8H2,(H,14,15,16)
- InChIKey
- GIZQLVPDAOBAFN-UHFFFAOYSA-N
- SMILES
- N1(CCN(CCO)CC1)CC(O)CS(=O)(=O)O
- CAS Datenbank
- 68399 · 68399-78-0(CAS DataBase Reference)
- EPA chemische Informationen
- 1 · 1-Piperazinepropanesulfonic acid, .beta.-hydroxy-4-(2-hydroxyethyl)- (68399-78-0)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H301 (90.5%): Toxic if swallowed [Danger Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 42 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information1-Piperazinepropanesulfonic acid, .beta.-hydroxy-4-(2-hydroxyethyl)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 3 (90.5%)
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29335995
- risk_code
- 25-36/37/38
- hazard_code
- T,Xi
- safety_code
- 26-36-45-24/25
Chemie und Industrie
Verwendung und Herstellung
General Manufacturing Information1-Piperazinepropanesulfonic acid, .beta.-hydroxy-4-(2-hydroxyethyl)-: INACTIVE
Anwendungen
VerwendenHEPPSO is a zwitterionic buffer used in GMP-manufacturing of advanced therapy medication products.
VerwendenHEPPSO shows no toxicity for crustaceans with which it has been studied and has been deemed suitable for toxicological studies. As an zwitterionic biological buffer, it often used in biological and biochemical research. It could used as an ampholytic separator to create a pH gradient in isoelectric focusing. HEPPSO is able to form radicals and is thus not suitable for redox reactions. It could forms a complex with Cu(II) ions so stability constants and concentrations should be taken into consideration when using this buffer in a solution containing copper ions. Although HEPPSO binds to coppers ions, it is still suitable for use as the bicinchoninic acid (BCA) assay. Diminished protein-induced color development can be accounted for or even eliminated through precipitating protein prior to reaction with bicinchoninic acid.
Anbieter100 Anbieter
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖北博杰生物科技有限公司0713-2060728 15629612610 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…