HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fluazacort
L-6400 · Azacortid · fluazacort · Fluazacortum · 21-acetoxy-9-fluoro-11β-hydroxy-2'-methyl-(16β)-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione · 9α-Fluoro-11β,21-dihydroxy-3,20-dioxo-1,4-pregnadieno[17α,16α-d]-2-Methyloxazoline 21-Acetate · (16β)-21-(Acetoxy)-9-fluoro-11β-hydroxy-2'-methylpregnano[17,16-d]oxazole-1,4-diene-3,20-dione · (5'β)-9-Fluoro-11β,21-dihydroxy-2'-methylpregnano[17,16-d]oxazole-1,4-diene-3,20-dione 21-acetate
Identifikatoren & physikalische Daten
| CAS No. | 19888-56-3 |
|---|---|
| Summenformel | C25H30FNO6 |
| Durchschnittliche Molmasse | 459,5 g/mol |
| Monoisotopische Masse | 459,20571584 g/mol |
| SMILES | CC(=O)OCC(=O)[C@@]12N=C(C)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C |
| InChIKey | BYZCJOHDXLROEC-RBWIMXSLSA-N |
| PubChem CID | 10072906 |
| ChEMBL | CHEMBL2107273 |
| ChEBI | CHEBI:135743 |
| EC No. | 243-400-2 |
| Lokaler Name | Fluazacort |
Chemische & physikalische Eigenschaften
| XLogP | 2,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 102 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 8 |
| Frei drehbare Bindungen | 4 |
| Schwere Atome | 33 |
| Formalladung | 0 |
| Komplexität | 1.050 |
| Arzneimittel | Pharmaceuticals -> Dermatologicals -> Corticosteroids, dermatological preparations |
| Schmelzpunkt | 252-255° |
| Siedepunkt | 592.379±50.00 °C(Press: 760.00 Torr)(predicted) |
| Dichte | 1.437±0.14 g/cm3(Temp: 25 °CPress: 760 Torr)(predicted) |
| pKa (Säurekonstante) | 13.138±0.70(predicted) |
Anwendungen & Verwendung
Verwenden
fluazacort is a glucucorticoid with anti-inflammatory properties used in the treatment of skin diseases.