5,8-Dihydroxy-1,4-naphthochinon

Naphthazarin

HCID 10141CAS 475-38-7
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
O=C1C=CC(=O)c2c(O)ccc(O)c21
InChIKey
RQNVIKXOOKXAJQ-UHFFFAOYSA-N
Summenformel
C10H6O4
Durchschnittliche Molmasse
190,15 g/mol
Monoisotopische Masse
190,02660867

Überblick

Naphthazarin is a naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups. It has a role as a geroprotector, an acaricide, an antibacterial agent, an antineoplastic agent, an apoptosis inducer and a plant metabolite.

Namen und Bezeichner

Bevorzugter Name
Naphthazarin
IUPAC
5,8-dihydroxynaphthalene-1,4-dione
Lokaler Name
5,8-Dihydroxy-1,4-naphthochinon
Englischer Name
5,8-Dihydroxy-1,4-naphthoquinone
Summenformel
C10H6O4
Molmasse
190.15

Namen und Synonyme

Naphthazarin5,8-Dihydroxy-1,4-naphthoquinone475-38-75,8-dihydroxynaphthalene-1,4-dioneNaphthazarineNaphthazarone5,8-Dihydroxynaphthoquinone5,8-Dihydroxy-1,4-naphthalenedione5,8-Dihydroxy-1,4-naphthosemiquinone1,4-NAPHTHOQUINONE, 5,8-DIHYDROXY-1,4-Naphthalenedione, 5,8-dihydroxy-S9IX5I5C0K
Weitere Namen anzeigen
NAPHTHAZALINEMordant Black 37Naphthazarin (6CI)5,8-Dihydroxy-1,4-nNaphthazarin, 10 mM in DMSO
5,8-dioxy-1,4-naphthoquinoneDTXSID00197161CHEBI:28849NSC-26647NSC-344555RefChem:831987DTXCID10119652207-495-4

Datenbank-Bezeichner

CAS
475-38-7
PubChem CID
10141
DTXSID
DTXSID00197161
ChEMBL
CHEMBL274056
ChEBI
CHEBI:28849
UNII
S9IX5I5C0K
EC Number
207-495-4
Nikkaji
J12.362E、J939.863E

Eigenschaften

Berechnete Struktureigenschaften

XLogP
1,8
Polarare Oberfläche (TPSA)
74,6 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
0
Schwere Atome
14

Experimentelle und physikochemische Eigenschaften

Chemical ClassesOther Uses -> Biochemical Research
SpringerMaterials PropertiesChemical shift
LogP1.79
Vapor Pressure0.0000001 [mmHg]
Physical DescriptionBrown solid; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
220 · 220-230 °C(lit.)
Siedepunkt
285.64 °C · 285.64°C (rough estimate)
Dichte
1.3366 · 1.3366 (rough estimate)
Brechungsindex
1.528 · 1.5280 (estimate)
storage temp.
Sealed in dry,Room Temperature
Aggregatzustand
powder to crystaline

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Hazards SummaryA skin and strong eye irritant; [Alfa Aesar MSDS]
Hazard Classes and CategoriesAcute Tox. 4 (33.3%)

Sicherheitsdaten

wgk
3
hs_code
2914409000
RTECS-Nr.
QL7970000
risk_code
36/37/38
hazard_code
Xi
safety_code
22-24/25-37/39-26

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationSubstances that inhibit or prevent the proliferation of NEOPLASMS.

Verwendung und Herstellung

UsesA fish toxin; [ChemIDplus]

Darstellung

synthetische1,8-Dinitronaphthalene and 1,5-Dinitronaphthalene mixture or both alone and one of sulfur 40% fuming sulfuric ACID reaction, the product (5, 8 – dihydroxy – naphthoquinone) into Sulfurous acidhydrogen salt.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups.

Zugehörige Reaktionen

2
Reaktionsaufzeichnung erstellen

Verknüpfte Notizen

Wird geladen…