2'-O-Methyladenosine
AMI · (2R,3R,4R,5R)-5-(6-AMino-9H-purin-9-yl)-2-(hydroxyMethyl)-4-Methoxytetrahydrofuran-3-ol · 2'-OMe-A · OMe-rA · cordysinin B · 2’-0MeA · 2'-OMe A · 2'-OMe-rA
Identifikatoren & physikalische Daten
| CAS No. | 2140-79-6 |
|---|---|
| Summenformel | C11H15N5O4 |
| Durchschnittliche Molmasse | 281,272 g/mol |
| Monoisotopische Masse | 281,11240396 g/mol |
| SMILES | CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21 |
| InChIKey | FPUGCISOLXNPPC-IOSLPCCCSA-N |
| PubChem CID | 102213 |
| ChEMBL | CHEMBL73237 |
| ChEBI | CHEBI:69426 |
| DTXSID | DTXSID50175671 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 200-202 C |
|---|---|
| Siedepunkt | 623.8±65.0 °C(Predicted) |
| Dichte | 1.84±0.1 g/cm3(Predicted) |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Löslichkeit | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Water (Slightly)Soluble in water. |
| Aggregatzustand | Powder |
| pKa (Säurekonstante) | 13.13±0.70(Predicted) |
| Farbe | White to Off-white |
| InChI | InChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1 |
| InChIKey | FPUGCISOLXNPPC-YGHVBYMHSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](OC)[C@@H]1O |
| CAS Datenbank | 2140-79-6(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Zollcode | 29349990 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36-24/25 |
Anwendungen & Verwendung
Beschreibung
2'-O-Methyladenosine (Cordysinin B) is a member of the class of adenosines that is adenosine in which the hydroxy group at position 2' is replaced by a methoxy group. It has been isolated from the mycelia of Cordyceps sinensis. It has a role as a fungal metabolite. It is a member of adenosines and an ether. It derives from an adenosine. analogue with antiviral properties, starting material for 2'-O'-methyl nucleotides. Potential metabolite of 2'-O-Me-cAMP.
Verwenden
2'-O-Methyladenosine is an analog of adenosine used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.