HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Azoxybenzol
Fentoxan · Azoxybenzol · ZOXYBENZENE · Azoxybenzeen · Azoxybenzide · Azoxybenzole · Azoxybenzene · Azoxylbenzene
Identifikatoren & physikalische Daten
| CAS No. | 20972-43-4 |
|---|---|
| Summenformel | C12H10N2O |
| Durchschnittliche Molmasse | 198,22 g/mol |
| Monoisotopische Masse | 198,07931294 g/mol |
| SMILES | [O-][N+](=Nc1ccccc1)c1ccccc1 |
| InChIKey | GAUZCKBSTZFWCT-UHFFFAOYSA-N |
| PubChem CID | 10316 |
| ChEMBL | CHEMBL1442921 |
| ChEBI | CHEBI:51865 |
| EC No. | 207-802-1 |
| DTXSID | DTXSID0024555 |
| Lokaler Name | Azoxybenzol |
Chemische & physikalische Eigenschaften
| XLogP | 3,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 41,1 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 15 |
| Formalladung | 0 |
| Komplexität | 216 |
| Stoffklassen | Nitrogen Compounds -> Other Aromatics (Nitrogen) |
| Dichte | 1.159 at 79 °F (NTP, 1992) - Denser than waterwill sink1.1590 @ 26 °C/4 °C1.16 |
| Color/Form | PALE YELLOW ORTHORHOMBIC NEEDLES |
| Löslichkeit | less than 1 mg/mL at 68 °F (NTP, 1992)INSOL IN WATERSOL IN ALCOHOL & ETHER43.5 G DISSOLVE IN 100 G PETROLEUM ETHER @ 15 °C |
| Siedepunkt | Decomposes (NTP, 1992)130 °C / 0.9mmHg |
| Decomposition | ...ON DECOMPOSITION IT EMITS TOXIC FUMES... |
| Schmelzpunkt | 97 °F (NTP, 1992)36 °C32-36 °C |
| Physical Description | Azoxybenzene appears as bright yellow crystals or yellowish-brown solid. (NTP, 1992)Yellow solidmp = 36 deg C[HSDB] Bright yellow or yellowish-brown solid[CAMEO] Orange solidmp = 33-36 deg C[Alfa Aesar MSDS] |
| Other Experimental Properties | 100 PARTS OF ABSOLUTE ALCOHOL SATURATED AT 16 °C CONTAIN 17.5 PARTS (WT/WT) AZOXYBENZENEEASILY VOLATILE IN SUPER-HEATED STEAM @ 140-150 °C |
| Brechungsindex | 1.6330 (estimate) |
| Lagerbedingungen | 0-6°C |
| Farbe | Yellow, rhombic crystals |
| Merck | 14,923 |
| BRN | 743984 |
| Dielektrizitätskonstante | 5.1(40℃) |
| Hauptanwendungen | agricultureenvironmental |
| InChI | 1S/C12H10N2O/c15-14(12-9-5-2-6-10-12)13-11-7-3-1-4-8-11/h1-10H/b14-13- |
| InChIKey | GAUZCKBSTZFWCT-YPKPFQOOSA-N |
| SMILES | [O-]\[N+](=N/c1ccccc1)c2ccccc2 |
| CAS Datenbank | 495-48-7(CAS DataBase Reference) |
| EPA chemische Informationen | Azoxybenzene (495-48-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302: Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P270, P271, P301+P317, P304+P340, P317, P330, and P501 (click each P-code to see the statement)H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
|---|---|
| Regulatorische Informationen | Azoxybenzene: Does not have an individual approval but may be used under an appropriate group standard |
| Brandgefahren | Flash point data for this chemical are not availablehowever, it is probably combustible. (NTP, 1992) |
| Brandpotenzial | SLIGHTLY DANGEROUS... |
| Gesundheitsgefahren | SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and eyes. Other symptoms include jaundice, cyanosis, dermatitis and liver and kidney damage. |
| Gefahrenübersicht | External application to rabbit eyes scored 1 on a scale of 1-10 (10 being most severe) for degree of injury after 24 hoursCauses icteric skin, methemoglobinemia, swelling of liver and spleen, and atrophy of testis and epididymis in oral studies of rats and miceEmergency treatment: Methemoglobinemia[HSDB] Dust mixtures with air may be explosiveA skin and eye irritantMay cause liver and kidney injury[CAMEO] Causes decrease in cellular immune response in intraperitoneal toxic-dose studies of ratsCauses other GI and liver changes in oral lethal-dose studies of mice[RTECS] May cause irritation and methemoglobinemia[Alfa Aesar MSDS] |
| Reaktive Gruppe | Azo, Diazo, Azido, Hydrazine, and Azide Compounds |
| Reactivity Profile | AZOXYBENZENE is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. |
| Air and Water Reactions | Dust may form an explosive mixture in air. Insoluble in water. |
| Hazard Classes and Categories | Acute Tox. 4 (100%)Acute toxicity - category 4Acute Tox. 4 * |
| Brandbekämpfung | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| Erste Hilfe | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Lagerbedingungen | MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS...SHOULD BE STORED IN A COOL WELL VENTILATED PLACE, OUT OF DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, AND SHOULD BE PERIODICALLY INSPECTED... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED... |
| Freisetung ohne Brand | SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| Unerwünschte Wirkungen | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
| Artificial Pollution Sources | AZOXYBENZENES MAY RESULT FROM THE CONDENSATION OF TWO MOLECULES OF PHENYLHYDROXYLAMINE, THE CONDENSATION OF PHENYLHYDROXYLAMINE WITH NITROBENZENE... /AZOXYBENZENES/KINETICS WERE STUDIED OF AZOBENZENE OXIDN BY OZONE IN AQ SOLN SIMULATING WASTEWATERS FROM DYE MFR. THE MAIN OXIDN PRODUCT WAS AZOXYBENZENE AND FORMATION PROCEEDED AS THE FIRST ORDER REACTION IN RESPECT TO OZONE. |
| Non-Human Toxicity Excerpts | RATED 1 ON RABBIT EYES...TESTED EXTERNALLY...AFTER 24 HR. THE MOST SEVERE INJURIES...RATED 10.WHEN ADMIN ORALLY TO RATS & MICE ICTERIC SKIN, METHEMOGLOBINEMIA, SWELLING OF SPLEEN & LIVER, & ATROPHY OF TESTIS & EPIDIDYMIS WERE OBSERVED. |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29153100 |
| RTECS-Nr. | CO4025000 |
| R-Sätze (R) | 20/22 |
| Toxizität | LD50 orl-rat: 620 mg/kg AMIHBC 10,61,54 |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 28A-28 |
| Lagerklasse | 10 - Combustible liquids |
| Gefahrstoffdaten | 495-48-7(Hazardous Substances Data) |
| Gefahrenklasse | Acute Tox. 4 InhalationAcute Tox. 4 Oral |
Anwendungen & Verwendung
Verwenden
Intermediate in organic synthesis.