HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diacetyldichlorofluorescein
H2DCFDA · 2',7'-DICHLORODIHYDROFLUORESCEIN DIACETATE · DCFH2-DA · 2',7'-DICHLOROFLUORESCEIN DIACETATE · MFCD 37501 · DCDHF DIACETATE · Synonyms: DCFH-DA · Diacetyldichlorofluoresce
Identifikatoren & physikalische Daten
| CAS No. | 2044-85-1 |
|---|---|
| Summenformel | C24H14Cl2O7 |
| Durchschnittliche Molmasse | 485,3 g/mol |
| Monoisotopische Masse | 484,0116582 g/mol |
| SMILES | CC(=O)Oc1cc2c(cc1Cl)C1(OC(=O)c3ccccc31)c1cc(Cl)c(OC(C)=O)cc1O2 |
| InChIKey | VQVUBYASAICPFU-UHFFFAOYSA-N |
| PubChem CID | 104913 |
| EC No. | 628-838-8 |
| DTXSID | DTXSID30174389 |
Chemische & physikalische Eigenschaften
| XLogP | 4,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 88,1 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 7 |
| Frei drehbare Bindungen | 4 |
| Schwere Atome | 33 |
| Formalladung | 0 |
| Komplexität | 775 |
| Schmelzpunkt | 232-234 °C(lit.) |
| Siedepunkt | 657.9±55.0 °C(Predicted) |
| Dichte | 1.59±0.1 g/cm3(Predicted) |
| Flammpunkt | >109℃ |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | DMSO: soluble |
| Aggregatzustand | Powder or Crystals |
| Farbe | Colorless to off-white |
| BRN | 68488 |
| InChI | InChI=1S/C24H14Cl2O7/c1-11(27)30-21-9-19-15(7-17(21)25)24(14-6-4-3-5-13(14)23(29)33-24)16-8-18(26)22(31-12(2)28)10-20(16)32-19/h3-10H,1-2H3 |
| InChIKey | VQVUBYASAICPFU-UHFFFAOYSA-N |
| SMILES | C12(C3=C(C=C(OC(C)=O)C(Cl)=C3)OC3=C1C=C(Cl)C(OC(C)=O)=C3)C1=C(C=CC=C1)C(=O)O2 |
Sicherheit & Vorschriften
| F | 3-8-10 |
|---|---|
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | 1759 |
| Zollcode | 29329990 |
| R-Sätze (R) | 36/37/38-34-20/22 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36-45-36/37/39 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Cell permeable, sensitive indicator of peroxynitrite formation. After hydrolysis of the diacetate groups by cytosolic esterases or base-catalyzed cleavage of the diacetate groups, DCDHF is oxidized by peroxynitrite yielding the highly fluorescent product