Skf 96365
Grundinformationen
- CAS
130495-35-1- Standard-SMILES
COc1ccc(CCCOC(Cn2ccnc2)c2ccc(OC)cc2)cc1.Cl- InChIKey
FWLPKVQUECFKSW-UHFFFAOYSA-N- Summenformel
- C22H27ClN2O3
- Durchschnittliche Molmasse
- 402,9 g/mol
- Monoisotopische Masse
- 402,1710204
Überblick
SKF-96365 hydrochloride is the hydrochloride salt of SKF-96365. It is a TRP channel blocker. It has a role as an autophagy inducer, a TRP channel blocker, an antineoplastic agent, a calcium channel blocker, a platelet aggregation inhibitor, a GABA antagonist and an apoptosis inducer. It contains a SKF-96365 free base(1+).
Namen und Bezeichner
- Bevorzugter Name
- Skf 96365
- IUPAC
- 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole;hydrochloride
- Englischer Name
- SKF 96365 hydrochloride
- Summenformel
- C22H27ClN2O3
- Molmasse
- 402.91
Namen und Synonyme
130495-35-1SKF-96365SKF96365SK&F 963651-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride33BI32858PSK&F-963651H-Imidazole, 1-(2-(4-methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-, monohydrochlorideRefChem:9318391-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole1-(2-(4-Methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)imidazoleSkf 96365
Weitere Namen anzeigen
CS-2170SKF 96365 HCISKF-96365, HCSKF-96365, HClSK AND F 96365SKF 96365 hydrochlorSKF 96365, TRP channel blocker
SKF 96365 HYDROCHLORIDESKF-96365 hydrochloride1-(2-(4-Methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole hydrochlorideSKF-96365 (hydrochloride)MFCD002364071-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole;hydrochloride1H-Imidazole, 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-, hydrochloride (1:1)1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole hydrochloride
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 45,5 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 10
- Schwere Atome
- 28
- Formalladung
- 0
- Komplexität
- 393
Physikochemische Eigenschaften
- Schmelzpunkt
- 119 °C · 119 °C
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- 2 O: · H2O: >20 mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Wasserlöslichkeit
- 100 mM · Soluble to 100mM in water
- Stabilität
- 1 year · Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
- InChI
- 1S/C22H26N2O3.ClH/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19;/h5-14,17,22H,3-4,15-16H2,1-2H3;1H
- InChIKey
- FWLPKVQUECFKSW-UHFFFAOYSA-N
- SMILES
- Cl.COc1ccc(CCCOC(Cn2ccnc2)c3ccc(OC)cc3)cc1
- CAS Datenbank
- 130495 · 130495-35-1(CAS DataBase Reference)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- 3
- hs_code
- 2933.29.4300
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Anwendungen
VerwendenSKF 96365 Hydrochloride is a novel inhibitor of receptor-mediated calcium entry.
Anbieter81 Anbieter
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…