3,8-Diamino-5-(3-(diethylmethylam-monio)-propyl)-6-phenylphenanthri-diniumdiiodid

Propidium Iodide

HCID 104981CAS 25535-16-4

Grundinformationen

Standard-SMILES
CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.[I-].[I-]
InChIKey
XJMOSONTPMZWPB-UHFFFAOYSA-M
Summenformel
C27H34I2N4
Durchschnittliche Molmasse
668,4 g/mol
Monoisotopische Masse
668,08729

Namen und Bezeichner

Bevorzugter Name
Propidium Iodide
IUPAC
3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium diiodide
Lokaler Name
3,8-Diamino-5-(3-(diethylmethylam-monio)-propyl)-6-phenylphenanthri-diniumdiiodid
Englischer Name
Propidium iodide
Summenformel
C27H34IN4+
Molmasse
541.5

Namen und Synonyme

propidium iodide25535-16-4Propidium diiodideCHEBI:51240TP416O228T3,8-Diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridinium diiodideDTXSID208940843,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodidePhenanthridinium, 3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-, diiodideNSC-169541Diiodide, PropidiumIodide, Propidium
Weitere Namen anzeigen
Propidium iodide solution3,8-DIAMINO-5-(3-DIETHYLAMINOPROPYL)-6-PHENYLPHENANTHRIDINIUM IODIDE METHIODIDEPI (Red)Nsc169541C27H34IN4PI solution-Cellstain-PiPI(Powder form)
RefChem:176408DTXCID101324125247-081-0Propidiumiodide3,8-Diamino-5-(3-(diethyl(methyl)ammonio)propyl)-6-phenylphenanthridin-5-ium iodidePropidium (Iodide)MFCD000119213-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium diiodide

Datenbank-Bezeichner

CAS
25535-16-4
PubChem CID
104981
DTXSID
DTXSID20894084
ChEBI
CHEBI:51240
UNII
TP416O228T
EC Number
247-081-0

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
55,9 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
7
Schwere Atome
33

Experimentelle und physikochemische Eigenschaften

Physical DescriptionDark red solid; [Sigma-Aldrich MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
220 · 220-225 °C (dec.) (lit.)
Dichte
1.5072 · 1.5072 (estimate)
storage temp.
2 · 2-8°C
Löslichkeit
Difficult to mix.
Aggregatzustand
Flaky Powder
Farbe
Dark red

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Warning

H315 (98.8%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (98.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (98.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H341 (26.1%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 165 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory InformationPhenanthridinium, 3,8-diamino-5-3-(diethylmethylammonio)propyl-6-phenyl-, diiodide: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummarySubcutaneous LD50 (mouse) = 16 mg/kg; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See Homidium bromide. See Iodine for the TLV of Iodides.
Hazard Classes and CategoriesSkin Irrit. 2 (98.8%);Eye Irrit. 2 (98.8%);STOT SE 3 (98.8%);Muta. 2 (26.1%)

Regulatorische Informationen

Regulatory InformationPhenanthridinium, 3,8-diamino-5-3-(diethylmethylammonio)propyl-6-phenyl-, diiodide: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

F
3-8-10-23
wgk
3
hs_code
29339900
RTECS-Nr.
SF7949600
risk_code
36/37/38-68-67-48/20/22-40-36/38-22-20-63
hazard_code
Xi,Xn

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 3 Einträge

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.

Verwendung und Herstellung

Uses · 1 Eintrag

Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits. [ChemIDplus]

Anwendungen · 1 Eintrag

VerwendenPropidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viab ility when used with other dyes that stain viable cells or cells that are early in the apoptosis process.

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北京华美互利生物化工010-56205725 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

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