beta-(N-Methylamino)-L-alanine

HCID 105089CAS 15920-93-1
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Grundinformationen

Standard-SMILES
CNC[C@H](N)C(=O)O
InChIKey
UJVHVMNGOZXSOZ-VKHMYHEASA-N
Summenformel
C4H10N2O2
Durchschnittliche Molmasse
118,13 g/mol
Monoisotopische Masse
118,07422757

Namen und Bezeichner

Bevorzugter Name
beta-(N-Methylamino)-L-alanine
IUPAC
(2S)-2-amino-3-(methylamino)propanoic acid
Englischer Name
3-(N-Methylamino)-L-alanine
Summenformel
C4H10N2O2
Molmasse
118.13

Namen und Synonyme

15920-93-1(S)-2-AMINO-3-(METHYLAMINO)PROPANOIC ACIDBMAAbeta-N-Methylamino-L-alanine(2S)-2-amino-3-(methylamino)propanoic acidL-Alanine, 3-(methylamino)-3-Methylamino-L-alanine108SA6URTVL-alpha-Amino-beta-(methylamino)propionic acidbeta-(N-Methylamino)-L-alanineBeta-Methylamino-L-alanineDTXSID60166611
Weitere Namen anzeigen
β-N-Methylamino-L-alanine(S)-BMAA-Methylamino-L-alanineB-METHYLAMINO-L-ALANINEβ-Methylamino-L-alanine--Methylamino-L-alanine
2-Amino-3(methylamino)propionic acidRefChem:917034DTXCID9089102(2S)-2-azaniumyl-3-(methylamino)propanoateL-Bmaa3-(Methylamino)-L-alanine3-(N-METHYLAMINO)-L-ALANINEMFCD08063270

Datenbank-Bezeichner

CAS
15920-93-1
PubChem CID
105089
DTXSID
DTXSID60166611
ChEMBL
CHEMBL11488
ChEBI
CHEBI:73169
UNII
108SA6URTV
Nikkaji
J82.463A

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-3,8
Polarare Oberfläche (TPSA)
75,4 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
3
Schwere Atome
8

Physikochemische Eigenschaften

Siedepunkt
284.2 · 284.2±30.0 °C(Predicted)
Dichte
1.157 · 1.157±0.06 g/cm3(Predicted)
storage temp.
2 · Sealed in dry,2-8°C
Löslichkeit
2 O: · H2O: solutions may be stored for several days at 4°Csoluble
Aggregatzustand
solid
pka
1.88 · 1.88±0.10(Predicted)

Sicherheit und Regulatorisches

Toxikologische Informationen

Health Effects · 1 Eintrag

BMAA is considered a possible cause of the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC). Its neurotoxic effects may include degenerative locomotor diseases resulting from damage to cells (such as neurons) in the motor cortex and spinal cord. (L1241)

Exposure RoutesOral (ingestion) (L1817) ; dermal (L1817)
Toxicity SummaryBMAA may cause neurotoxic effects by damaging cells (such as neurons) in the motor cortex and spinal cord. (L1241)
Signs and SymptomsSymptoms of BMAA exposure may include limb muscle atrophy and behavioral dysfunction. (L1241)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

Sicherheitsdaten

wgk
3
hs_code
2922498590
safety_code
22-24/25
hazard_class
IRRITANT

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationDrugs that bind to and activate excitatory amino acid receptors.

Verwendung und Herstellung

UsesMethylamino-L-alanine, beta- is a plant toxin found in the seeds of the cycad (division Cycadophyta). (L1241)

Anbieter50 Anbieter

武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens is replaced by a methylamino group. A non-proteinogenic amino acid produced by cyanobacteria, it is a neurotoxi that has been postulated as a possible cause of neurodegenerative disorders of aging such as Alzheimer's disease, amyotrophic lateral sclerosis, and the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS-PDC) syndrome of Guam.

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