Grundinformationen
- Standard-SMILES
Cc1ncc(CO)c(CN)c1O.Cl.Cl- InChIKey
HNWCOANXZNKMLR-UHFFFAOYSA-N- Summenformel
- C8H14Cl2N2O2
- Durchschnittliche Molmasse
- 241,11 g/mol
- Monoisotopische Masse
- 240,04323305
Überblick
Pyridoxamine dihydrochloride is a hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy. It has a role as an iron chelator, a mouse metabolite, a Saccharomyces cerevisiae metabolite, a nephroprotective agent, a plant metabolite, an Escherichia coli metabolite and a human metabolite. It is a vitamin B6 and a hydrochloride. It contains a pyridoxamine(2+).
Namen und Bezeichner
- Bevorzugter Name
- Pyridoxamine, dihydrochloride
- IUPAC
- 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol;dihydrochloride
Namen und Synonyme
PYRIDOXAMINE DIHYDROCHLORIDE524-36-7Pyridoxylamine dihydrochloride4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochlorideYQ8NCR7V0ODTXSID60450882-Methyl-3-hydroxy-4-aminomethyl-5-hydroxymethylpyridene dihydrochlorideDTXCID4025088CHEBI:131532PYRIDOXAMINE, MONOHYDROCHLORIDENSC-21278Pyridoxamine, dihydrochloride
Weitere Namen anzeigen
RefChem:870905208-357-64-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol dihydrochloridePyridoxamine 2HClPyridorinPyridoxamine dichlorohydratePyridoxylamine (dihydrochloride)pyridoxaminedihydrochloride
Datenbank-Bezeichner
- CAS
524-36-7- PubChem CID
- 10664
- DTXSID
DTXSID6045088- ChEMBL
CHEMBL2361504- ChEBI
CHEBI:131532- UNII
- YQ8NCR7V0O
- EC Number
- 208-357-6
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 79,4 Ų
- H-Brücken-Donoren
- 5
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 14
- Formalladung
- 0
- Komplexität
- 143
Experimentelle und physikochemische Eigenschaften
Chemical ClassesBiological Agents -> Vitamins and Derivatives
Vapor Pressure0.00000144 [mmHg]
Physical DescriptionSolid; [Merck Index] White to off-white solid; [Acros Organics MSDS]
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Warning
H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 43 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazards SummaryCauses convulsions in oral and subcutaneous lethal-dose studies of mice and rats; [RTECS] An irritant; [Acros Organics MSDS] See Pyridoxine hydrochloride.
Hazard Classes and CategoriesSkin Irrit. 2 (97.7%)
Chemie und Industrie
Verwendung und Herstellung
UsesThe 4-aminomethyl form of VITAMIN B 6. During transamination of amino acids, PYRIDOXAL PHOSPHATE is transiently converted into pyridoxamine phosphate. [ChemIDplus]
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