HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide
4-Methyl-3-oxo-N-(4-benzyloxyphenyl)-2-[1-phenyl-2-(4-fluorophenyl)-2-oxoethyl]pentaMide · 4-Fluoro-α-(2-Methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[4-(phenylMethoxy)phenyl]benzenebutanaMide · Benzenebutanamide, 4-fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[4-(phenylmethoxy)phenyl]- · 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide
![Molekülstruktur von 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide](/img/chemical/10697370.png)
Identifikatoren & physikalische Daten
| CAS No. | 163217-67-2 |
|---|---|
| Summenformel | C33H30FNO4 |
| Durchschnittliche Molmasse | 523,6 g/mol |
| Monoisotopische Masse | 523,2158866 g/mol |
| SMILES | CC(C)C(=O)C(C(=O)Nc1ccc(OCc2ccccc2)cc1)C(C(=O)c1ccc(F)cc1)c1ccccc1 |
| InChIKey | GQGGAQUHBXLZMT-UHFFFAOYSA-N |
| PubChem CID | 10697370 |
| DTXSID | DTXSID90443609 |
Chemische & physikalische Eigenschaften
| XLogP | 7,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 72,5 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 11 |
| Schwere Atome | 39 |
| Formalladung | 0 |
| Komplexität | 788 |
| Löslichkeit | soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate |
| Aggregatzustand | Solid |
| Farbe | Off-White |
Anwendungen & Verwendung
Verwenden
A intermediate of the metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.