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Benzidindihydrochlorid

Benzidine dihydrochloride

HCID 10754
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Grundinformationen

CAS
531-85-1
Standard-SMILES
Cl.Cl.Nc1ccc(-c2ccc(N)cc2)cc1
InChIKey
RUAXWVDEYJEWRY-UHFFFAOYSA-N
Summenformel
C12H12N2.2ClH
Durchschnittliche Molmasse
257,16 g/mol
Monoisotopische Masse
256,0534038

Überblick

Benzidine dihydrochloride is a white crystalline powder. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
Benzidine dihydrochloride
IUPAC
4-(4-aminophenyl)aniline;dihydrochloride
Lokaler Name
Benzidindihydrochlorid
Englischer Name
Benzidine dihydrochloride
Summenformel
C12H13ClN2
Molmasse
220.7

Namen und Synonyme

BENZIDINE DIHYDROCHLORIDE531-85-1Benzidine HClDihidrocloruro de benzidina[1,1'-Biphenyl]-4,4'-diamine, dihydrochlorideDTXSID7020138LVU06XHC39(1,1'-Biphenyl)-4,4'-diamine, dihydrochlorideDTXCID10138(1,1'-Biphenyl)-4,4'-diamine, hydrochloride (1:2)NSC-3500RefChem:118133
Weitere Namen anzeigen
BENZIDINE HYDROCHLORIDEbenzidine2hclBenzidine dihydrochlPiroctone Impurity 1dihidroclorurodebenzidinaBenzidine dihydroenloridePhenylbutazone Impurity E
(1,1'-Biphenyl)-4,4'-diamine hydrochloride (1:2)208-519-6Benzidine.2HCl4-(4-aminophenyl)aniline;dihydrochloridePhenylbutazone Impurity Abiphenyl-4,4'-diamine dihydrochloridePhenylbutazone Impurity N2benzidinedihydrochloride

Datenbank-Bezeichner

CAS
531-85-1
PubChem CID
10754
DTXSID
DTXSID7020138
ChEMBL
CHEMBL3184470
UNII
LVU06XHC39
EC Number
208-519-6

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
52 Ų
H-Brücken-Donoren
4
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
1
Schwere Atome
16
Formalladung
0
Komplexität
145

Experimentelle und physikochemische Eigenschaften

Chemical Classes · 2 Einträge

Nitrogen Compounds -> Benzidine and Derivatives

Carcinogens

Solubility1 to 5 mg/mL at 74.3 °F (NTP, 1992)
Melting Pointgreater than 572 °F (NTP, 1992)
Vapor Pressure0.00000438 [mmHg]
Physical Description · 2 Einträge

Benzidine dihydrochloride is a white crystalline powder. (NTP, 1992)

White solid; [CAMEO] Colorless crystalline solid; [MSDSonline]

Physikochemische Eigenschaften

Schmelzpunkt
300 °C · ≥300 °C
Aggregatzustand
powder
Farbe
Leaflets
Wasserlöslichkeit
0.1 · 0.1-0.5 g/100 mL at 23.5 ºC
BRN
3914846 · 3914846
InChI
InChI=1S/C12H12N2.ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;/h1-8H,13-14H2;1H
InChIKey
FYRTZXXTIDKEJD-UHFFFAOYSA-N
SMILES
NC1C=CC(C2C=CC(N)=CC=2)=CC=1.Cl
CAS Datenbank
531 · 531-85-1(CAS DataBase Reference)
EPA chemische Informationen
Benzidine dihydrochloride (531-85-1)

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P203, P264, P270, P273, P280, P301+P317, P318, P330, P391, P405, and P501 (click each P-code to see the statement)

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P203, P264, P270, P273, P280, P301+P317, P318, P330, P391, P405, and P501 (click each P-code to see the statement)

Gefahrenhinweise

Regulatory Information · 4 Einträge

Hazard Traits - Carcinogenicity

S - indicates a substance that is identified in a final Significant New Use Rule.

[1,1'-Biphenyl]-4,4'-diamine, dihydrochloride: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of exposure to this compound include nausea, vomiting, liver damage and kidney damage.
Hazards SummaryReadily absorbed through skin; Symptoms of exposure to this compound include nausea, vomiting, liver damage and kidney damage. [CAMEO] May cause irritation; Targets the liver, kidneys, and bladder; [MSDSonline] See Benzidine.
Reactive GroupSalts, Acidic
Reactivity Profile · 1 Eintrag

Acidic organic/inorganic salts, such as BENZIDINE DIHYDROCHLORIDE, are generally soluble in water. The resulting solutions contain moderate to high concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Air and Water ReactionsThis chemical may be sensitive to prolonged exposure to light and air. Slightly soluble in water.
Hazard Classes and Categories · 4 Einträge

Acute Tox. 4 (100%)

Carcinogenicity - category 1A

Carcinogens

Carc. 1A

Sicherheit und Schutzausrüstung

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Toxikologische Informationen

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Sicherheitsdaten

wgk
3
tsca
TSCA listed
ridadr
UN 2811 6.1/PG 2
RTECS-Nr.
DD0600000
risk_code
45-22-50/53-36/37/38-20/21/22
Toxizität
mmo-sat 100 nmol/plate MUREAV 136,33,84
hazard_code
T,N,Xn
safety_code
53-45-60-61-36-26
Speicherklasse
6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1Carc. 1A

Chemie und Industrie

Verwendung und Herstellung

UsesIn the presence of acids, benzidine forms salts such as benzidine dihydrochloride. The dihydrochloride form hydrolyzes into the monohydrochloride salt and hydrochloric acid. [Ullmann]
General Manufacturing Information[1,1'-Biphenyl]-4,4'-diamine, hydrochloride (1:2): ACTIVE

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